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- Table of Contents
KDR Antibodies
AND KDR ELISA kits, KDR Proteins
Many biological assays use antibodies to detect KDR, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with KDR in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop KDR antibodies...
Designing a Western blot for KDR? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the KDR Western Blot GuideKDR Infographic by Boster Bio
All KDR Products
Product
Figures
Specificity
Applications
Price
Anti-VEGF Receptor 2/Kdr Antibody Picoband®
20 Citations
Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A00901-3
100 μg/vial
Cat # A00901-3
100 μg/vial
Anti-VEGF Receptor 2/KDR Antibody Picoband®
5 Citations
Human
Flow Cytometry, IHC, ICC, WB
$370
Cat # A00901-2
100 μg/vial
Cat # A00901-2
100 μg/vial
Human
ELISA
$499
Cat # EK0544
96 wells/kit, with removable strips.
Cat # EK0544
96 wells/kit, with removable strips.
Mouse
ELISA
$499
Cat # EK0590
96 wells/kit, with removable strips.
Cat # EK0590
96 wells/kit, with removable strips.
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00901-3
100 μg
Cat # M00901-3
100 μg
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00901-8
100 μg
Cat # M00901-8
100 μg
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00901-7
100 μg
Cat # M00901-7
100 μg
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00901-6
100 μg
Cat # M00901-6
100 μg
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00901-5
100 μg
Cat # M00901-5
100 μg
Human, Mouse, Rat
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00901-4
100 μg
Cat # M00901-4
100 μg
Enzyme Activity, SDS-PAGE
$243
Cat # PROTQ16881
Starting from 20ug
Cat # PROTQ16881
Starting from 20ug
Human, Mouse, Rat
IF, IHC, ICC, WB
$482
Cat # A00901Y1214
100ul
Cat # A00901Y1214
100ul
Human, Mouse, Rat
ELISA, IF, IHC, WB
$380
Cat # A00901Y1175-1
100ul
Cat # A00901Y1175-1
100ul
Human, Mouse, Rat
ELISA, IF, IHC
$380
Cat # A00901Y1054Y1063
100ul
Cat # A00901Y1054Y1063
100ul
Human, Mouse, Rat
ELISA
$540
Cat # EKC2539
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2539
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2538
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2538
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2133
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2133
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$480
Cat # EKC1594
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1594
1 kit, containing one 96-well plate and all necessary reagents
Human
$960
Cat # LS003791
20 µg, 100 µg
Cat # LS003791
20 µg, 100 µg
KDR Overview
Facts about Vascular endothelial growth factor receptor 2.
Vascular endothelial growth factor receptor 2 (KDR)
Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFC and VEGFD. Plays an essential role in the regulation of angiogenesis, vascular development, vascular permeability, and embryonic hematopoiesis.
Promotes proliferation, survival, migration and differentiation of endothelial cells. Promotes reorganization of the actin cytoskeleton.
Gene Information
| Human | |
|---|---|
| Gene Name: | KDR |
| Uniprot: | P35968 |
| Entrez: | 3791 |
Family
| Belongs to: |
|---|
| protein kinase superfamily |
Alternative Names
CD309 antigen; CD309; EC 2.7.10; EC 2.7.10.1; Fetal liver kinase 1; fetal liver kinase-1; Flk1; Flk-1; FLK1tyrosine kinase growth factor receptor; KDR; kinase insert domain receptor (a type III receptor tyrosine kinase); Kinase insert domain receptor; KRD1; Ly73; Protein-tyrosine kinase receptor flk-1; soluble VEGFR2; vascular endothelial growth factor receptor 2; VEGF R2; VEGFR; VEGFR2; VEGFR-2
Molecular Weight
Mass (kDA):
151.527 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 4q12 |
| Sequence: | 4; NC_000004.12 (55078481..55125595, complement) |
Tissue Specificity
Detected in cornea (at protein level). Widely expressed.
Subcellular Localizations
Cell junction. Endoplasmic reticulum. Localized with RAP1A at cell-cell junctions (By similarity). Colocalizes with ERN1 and XBP1 in the endoplasmic reticulum in endothelial cells in a vascular endothelial growth factor (VEGF)-dependent manner (PubMed:23529610).; [Isoform 1]: Cell membrane; Single-pass type I membrane protein. Cytoplasm. Nucleus. Cytoplasmic vesicle. Early endosome. Detected on caveolae-enriched lipid rafts at the cell surface. Is recycled from the plasma membrane to endosomes and back again. Phosphorylation triggered by VEGFA binding promotes internalization and subsequent de
Diseases
- Tumor Angiogenesis
- Neoplasms
- Pathologic Neovascularization
- Malignant Neoplasms
- Carcinoma
- Neoplasm Metastasis
- Malaria
- Hypoxia
- Tissue Adhesions
- Malignant Paraganglionic Neoplasm
- Mammary Neoplasms
- Malignant Neoplasm Of Breast
Interacting Proteins
- CRK
- FLT4
- GREM1
- HSPG2
- ITGA2
- LGALS1
- LRP8
- MET
- NCK1
- NRP1
Pathways
- Angiogenesis
- Cell Proliferation
- Insecticide Resistance
- Cell Growth
- Pyrethroid Resistance
- Endothelial Cell Proliferation
- Tube Formation
- Pathogenesis
- Vasculogenesis
- Secretion
- Localization
- Cell Migration
- Regeneration
PTMs
- Phosphorylation
- Acetylation
- Cleavage
- Methylation
- Dephosphorylation
- Glycosylation
- Oxidation
- Phosphorothioation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/KDR
bosterbio.com/bosterbio-gene-info-cards/KDR
References
PMID: 18593464 by Jin P., et al. Novel splice variants derived from the receptor tyrosine kinase superfamily are potential therapeutics for rheumatoid arthritis.
PMID: 19668192 by Albuquerque R.J., et al. Alternatively spliced vascular endothelial growth factor receptor-2 is an essential endogenous inhibitor of lymphatic vessel growth.
22 Publications of Boster KDR Antibodies & ELISA Kits
- PubMed ID: PMID:25550894, Fructopyrano-(1→4)-glucopyranose inhibits the proliferation of liver cancer ce...
- PubMed ID: 10.5021/ad.2016.28.1.30, Genetic Risk Factors for Psoriasis in Turkish Population: -1540 C/A, -1512 Ins18...
- PubMed ID: 10.3892/etm.2014.1780, Effects of propranolol and isoproterenol on infantile hemangioma endothelial cel...
- PubMed ID: 10.3727/096368916X691123, Activation of Endogenous Cardiac Stem Cells by Apelin-13 in Infarcted Rat Heart:
- PubMed ID: 10.18632/oncotarget.15274, eIF3i activity is critical for endothelial cells in tumor induced angiogenesis t...
- PubMed ID: 10.1016/j.peptides.2012.02.006, Ghrelin promotes the differentiation of human embryonic stem cells in infarcted ...
- PubMed ID: 10.1016/j.jaad.2019.03.055, Vascular endothelial growth factor gene polymorphisms in patients with rosacea: ...
- PubMed ID: 10.1016/j.bioorg.2018.12.040, Synthesis, anticancer effect and molecular modeling of new thiazolylpyrazolyl co...
- PubMed ID: 10.1016/j.bbr.2016.12.037, Epigallocatechin-3-gallate promotes angiogenesis via up-regulation of Nfr2 signa...
- PubMed ID: 10.1002/cbin.10679, Infarcted cardiac microenvironment may hinder cardiac lineage differentiation of...
- PubMed ID: 33224751, Kong Z,Chen M,Jiang J,Zhu J,Liu Y. A new method of culturing rat bone marrow end...
- PubMed ID: 30355935, Role of the HIF%u20111 signaling pathway in chronic obstructive pulmonary diseas...
- PubMed ID: 28193911, eIF3i activity is critical for endothelial cells in tumor induced angiogenesis t...
- PubMed ID: 27221035, A novel multi-target RNAi adenovirus inhibits hepatoma cell proliferation, migra...
- PubMed ID: 26848216, Genetic Risk Factors for Psoriasis in Turkish Population: -1540 C/A, -1512 Ins18...
- PubMed ID: 28791301, Yan-Ping D, Xiao-Qin G, Xiao Ping M, Ying Quan Y. Biomed Res Int. 2017;2017:2597...
- PubMed ID: 25009634, Zhu Y, Tuerxun A, Hui Y, Abliz P. Exp Ther Med. 2014 Aug;8(2):647-651. Epub 2014...
- PubMed ID: 22710477, Sun Y, Chen S, Song G, Ren L, Wei L, Liu N, Zhang D, Lv X. Int J Mol Med. 2012 S...
- PubMed ID: 25550894, Liu M, Yang S, Zhang D, Shui P, Song S, Yao J, Dai Y, Sun Q. Int J Clin Exp Med....
- PubMed ID: 22101081, Fu Y, Zhao Z, Wu Y, Wu K, Xu X, Liu Y, Tong C. J Ethnopharmacol. 2012 Jan 6;139(...
- PubMed ID: 23946799, Wang L, Liu X, Wang H, Wang S. Oncol Lett. 2013 Jul;6(1):175-180. Epub 2013 May ...
*Showing only the more recent 20. More publications can be found for each product on its corresponding product page