LRP chaperone MESD Antibodies

AND MESD ELISA kits, LRP chaperone MESD Proteins

Many biological assays use antibodies to detect LRP chaperone MESD, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with LRP chaperone MESD in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop LRP chaperone MESD antibodies...

We validate the specificity of these antibodies to LRP chaperone MESD by testing them on tissues known to express MESD positively and negatively. Browse below to find the MESD antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MESD Infographic by Boster Bio

All MESD Products

Product

Figures

Specificity

Applications

Price

Anti-MESDC2 Antibody

Human, Mouse

$405
Cat # A32230
100ul

Human MESDC2 Recombinant Protein

SDS-PAGE

$265
Cat # PROTQ14696
Starting from 20ug

Mouse MESDC2 Recombinant Protein

SDS-PAGE

$250
Cat # PROTQ9ERE7
Starting from 4ug

Anti-MESDC2/MESD Antibody Picoband™

Human

ELISA, Flow Cytometry, WB

$370
Cat # A32230-1
100 μg/vial

MESD (NM_015154) Human Over-expression Lysate

Human

$628
Cat # LS023184
100 µg

MESD Overview

Facts about LRP chaperone MESD.

MESD 3D structure. Source: alphafold

LRP chaperone MESD (MESD)

Chaperone specifically assisting the folding of beta- propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). Acts as a modulator of the Wnt pathway via chaperoning the coreceptors of the canonical Wnt pathway, LRP5 and LRP6, to the plasma membrane.

Essential for specification of embryonic polarity and mesoderm induction. Plays an important role in neuromuscular junction (NMJ) formation by promoting cell- surface expression of LRP4 (By similarity).

Gene Information

Human
Gene Name:	MESD
Uniprot:	Q14696
Entrez:	23184

Family

Belongs to:

MESD family

Alternative Names

LRP chaperone MESD

Molecular Weight

Mass (kDA):
26.077 kDA

Genomic Context


Human

Location:	15q25.1
Sequence:	15; NC_000015.10 (80946289..80989819, complement)

Subcellular Localizations

Endoplasmic reticulum. Released from apoptotic cells and shed photoreceptor outer segments.

PTMs

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MESD

References

PMID: 15014448 by Culi J., et al. Boca-dependent maturation of beta-propeller/EGF modules in low- density lipoprotein receptor proteins.

PMID: 17488095 by Koduri V., et al. Requirement for natively unstructured regions of mesoderm development candidate 2 in promoting low-density lipoprotein receptor-related protein 6 maturation.