N-alpha-acetyltransferase 10 (NAA10)

Catalytic subunit of the N-terminal acetyltransferase A (NatA) complex which displays alpha (N-terminal) acetyltransferase activity (PubMed:15496142, PubMed:19826488, PubMed:19420222, PubMed:20145209, PubMed:27708256, PubMed:25489052). Acetylates amino termini which are devoid of initiator methionine (PubMed:19420222).

The alpha (N-terminal) acetyltransferase activity might be important for vascular, hematopoietic and neuronal growth and development. Without NAA15, screens epsilon (internal) acetyltransferase activity towards HIF1A, thereby promoting its degradation (PubMed:12464182).