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- Table of Contents
NAA10 Antibodies
AND NAA10 ELISA kits, NAA10 Proteins
Many biological assays use antibodies to detect NAA10, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NAA10 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NAA10 antibodies...
Designing an IHC experiment for NAA10? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the NAA10 IHC GuideNAA10 Infographic by Boster Bio
All NAA10 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
IF, IHC, ICC, WB
$405
Cat # A02890
100ul
Cat # A02890
100ul
NAA10 Overview
Facts about N-alpha-acetyltransferase 10.
N-alpha-acetyltransferase 10 (NAA10)
Catalytic subunit of the N-terminal acetyltransferase A (NatA) complex which displays alpha (N-terminal) acetyltransferase activity (PubMed:15496142, PubMed:19826488, PubMed:19420222, PubMed:20145209, PubMed:27708256, PubMed:25489052). Acetylates amino termini which are devoid of initiator methionine (PubMed:19420222).
The alpha (N-terminal) acetyltransferase activity might be important for vascular, hematopoietic and neuronal growth and development. Without NAA15, screens epsilon (internal) acetyltransferase activity towards HIF1A, thereby promoting its degradation (PubMed:12464182).
Gene Information
| Human | |
|---|---|
| Gene Name: | NAA10 |
| Uniprot: | P41227 |
| Entrez: | 8260 |
Family
| Belongs to: |
|---|
| acetyltransferase family |
Alternative Names
ARD1 homolog A, N-acetyltransferase (S. cerevisiae); ARD1 homolog, N-acetyltransferase (S. cerevisiae); ARD1; ARD1AARD1 homolog, N-acetyltransferase; EC 2.3.1.-; EC 2.3.1.88; MGC71248; N(alpha)-acetyltransferase 10, NatA catalytic subunit; N-acetyltransferase ARD1, human homolog of; N-acetyltransferase; N-alpha-acetyltransferase 10, NatA catalytic subunit; N-terminal acetyltransferase complex ARD1 subunit homolog A
Molecular Weight
Mass (kDA):
26.459 kDA
Genomic Context
| Human | |
|---|---|
| Location: | Xq28 |
| Sequence: | X; NC_000023.11 (153929225..153935037, complement) |
Tissue Specificity
Ubiquitous.
Subcellular Localizations
Cytoplasm. Nucleus. Also present in the free cytosolic and cytoskeleton-bound polysomes.
Diseases
- Malignant Neoplasms
- Neoplasms
- Malignant Neoplasm Of Breast
- Hypoxia
- Cell Transformation, Neoplastic
- Malignant Neoplasm Of Lung
- Lung Neoplasms
- Neoplasm Metastasis
- Carcinoma
- Mammary Neoplasms
- Tumor Angiogenesis
- Carcinogenesis
Interacting Proteins
- ARHGEF6
- ARHGEF7
- Arhgef7
- CALCOCO2
- CEP44
- FIP1L1
- KIFAP3
- KRTAP10-5
- KRTAP10-7
- MEOX2
Pathways
- Cell Proliferation
- Cell Cycle
- Cell Growth
- Angiogenesis
- Localization
- Translation
- Protein Acetylation
- Cell Migration
- Induction Of Apoptosis
- Methylation
- Rna Interference
- Oncogenesis
- Gene Silencing
PTMs
- Acetylation
- Phosphorylation
- Ubiquitination
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NAA10
bosterbio.com/bosterbio-gene-info-cards/NAA10
References
PMID: 7981673 by Tribioli C., et al. Isolation of new genes in distal Xq28: transcriptional map and identification of a human homologue of the ARD1 N-acetyl transferase of Saccharomyces cerevisiae.
PMID: 15496142 by Arnesen T., et al. Identification and characterization of the human ARD1-NATH protein acetyltransferase complex.