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- Table of Contents
Facts about N-alpha-acetyltransferase 10.
The alpha (N-terminal) acetyltransferase activity might be important for vascular, hematopoietic and neuronal growth and development. Without NAA15, screens epsilon (internal) acetyltransferase activity towards HIF1A, thereby promoting its degradation (PubMed:12464182).
Human | |
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Gene Name: | NAA10 |
Uniprot: | P41227 |
Entrez: | 8260 |
Belongs to: |
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acetyltransferase family |
ARD1 homolog A, N-acetyltransferase (S. cerevisiae); ARD1 homolog, N-acetyltransferase (S. cerevisiae); ARD1; ARD1AARD1 homolog, N-acetyltransferase; EC 2.3.1.-; EC 2.3.1.88; MGC71248; N(alpha)-acetyltransferase 10, NatA catalytic subunit; N-acetyltransferase ARD1, human homolog of; N-acetyltransferase; N-alpha-acetyltransferase 10, NatA catalytic subunit; N-terminal acetyltransferase complex ARD1 subunit homolog A
Mass (kDA):
26.459 kDA
Human | |
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Location: | Xq28 |
Sequence: | X; NC_000023.11 (153929225..153935037, complement) |
Ubiquitous.
Cytoplasm. Nucleus. Also present in the free cytosolic and cytoskeleton-bound polysomes.
PMID: 7981673 by Tribioli C., et al. Isolation of new genes in distal Xq28: transcriptional map and identification of a human homologue of the ARD1 N-acetyl transferase of Saccharomyces cerevisiae.
PMID: 15496142 by Arnesen T., et al. Identification and characterization of the human ARD1-NATH protein acetyltransferase complex.