NMRK2 Antibodies

AND NMRK2 ELISA kits, NMRK2 Proteins

Many biological assays use antibodies to detect NMRK2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NMRK2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NMRK2 antibodies...

We validate the specificity of these antibodies to NMRK2 by testing them on tissues known to express NMRK2 positively and negatively. Browse below to find the NMRK2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NMRK2 Infographic by Boster Bio

All NMRK2 Products

Product

Figures

Specificity

Applications

Price

Human ITGB1BP3 Recombinant Protein

SDS-PAGE

$250
Cat # PROTQ9NPI5
Starting from 4ug

Anti-ITGB1BP3 (NMRK2) Mouse Monoclonal Antibody [Clone ID: OTI1A12]

Human, Mouse

$523
Cat # M12121
100 µl

NMRK2 Overview

Facts about Nicotinamide riboside kinase 2.

NMRK2 3D structure. Source: alphafold

Nicotinamide riboside kinase 2 (NMRK2)

Catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN) and nicotinic acid mononucleotide (NaMN). Reduces laminin matrix deposition and cell adhesion to laminin, but not to fibronectin.

Involved in the regulation of PXN in the protein level and of PXN tyrosine phosphorylation. May play a role in the regulation of terminal myogenesis.

Gene Information

Human
Gene Name:	NMRK2
Uniprot:	Q9NPI5
Entrez:	27231

Family

Belongs to:

uridine kinase family

Alternative Names

EC 2.7.1.22; EC 2.7.1.n4; integrin beta 1 binding protein 3; Integrin beta-1-binding protein 3; MGC126624; MIBPNRK 2; Muscle integrin-binding protein; muscle-specific beta 1 integrin binding protein; nicotinamide riboside kinase 2; Nicotinic acid riboside kinase 2; NmR-K 2; NRK2RNK 2; Ribosylnicotinamide kinase 2; Ribosylnicotinic acid kinase 2

Molecular Weight

Mass (kDA):
26.046 kDA

Genomic Context


Human

Location:	19p13.3
Sequence:	19; NC_000019.10 (3933103..3942416)

Tissue Specificity

Predominantly expressed in skeletal muscle and, at a much lower level, in the heart (at protein level). No expression in brain, kidney, liver, lung, pancreas nor placenta.

Diseases

Malignant Neoplasms
Neoplasms
Tissue Adhesions

Interacting Proteins

LRP12

Pathways

Cell Adhesion
Aging
Endocytosis

Research Areas

Cancer
Cell Biology
Cellular Markers
Cytokine Research
Immunology

Mesenchymal Stem Cell Markers
Neuronal Cell Markers
Signal Transduction
Stem Cell Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NMRK2

References

PMID: 10613898 by Li J., et al. A novel muscle-specific beta 1 integrin binding protein (MIBP) that modulates myogenic differentiation.

PMID: 15137942 by Bieganowski P., et al. Discoveries of nicotinamide riboside as a nutrient and conserved NRK genes establish a Preiss-Handler independent route to NAD+ in fungi and humans.