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Gnmt Antibodies
AND Gnmt ELISA kits, Gnmt Proteins
Many biological assays use antibodies to detect Gnmt, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Gnmt in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Gnmt antibodies...
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Gnmt Infographic by Boster Bio
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Gnmt Overview
Facts about Glycine N-methyltransferase.
Glycine N-methyltransferase (Gnmt)
Catalyzes the methylation of glycine by using S- adenosylmethionine (AdoMet) to form N-methylglycine (sarcosine) with the concomitant creation of S-adenosylhomocysteine (AdoHcy). Possible crucial role in the regulation of tissue concentration of AdoMet and of metabolism of methionine (By similarity).
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Gene Information
| Mouse | |
|---|---|
| Gene Name: | Gnmt |
| Uniprot: | Q9QXF8 |
| Entrez: | 14711 |
Family
| Belongs to: |
|---|
| class I-like SAM-binding methyltransferase superfamily |
Alternative Names
EC 2.1.1.20; Glycine NMethyltransferase; Glycine N-Methyltransferase; GNMT
Molecular Weight
Mass (kDA):
32.675 kDA
Genomic Context
| Mouse | |
|---|---|
| Location: | 17 22.9 cM|17 C |
| Sequence: | 17; |
Diseases
- Liver Carcinoma
- Carcinoma
- Malignant Neoplasms
- Liver Diseases
- Liver Neoplasms
- Neoplasms
- Diabetes Mellitus
- Malignant Neoplasm Of Liver
- Folic Acid Deficiency
- 5,10-methylenetetrahydrofolate Reductase Deficiency
- Hepatic Methionine Adenosyltransferase Deficiency
- Hepatitis
- Steatohepatitis
Pathways
- Methylation
- Dna Methylation
- Transsulfuration
- Pathogenesis
- Gluconeogenesis
- Dna Hypomethylation
- Cell Cycle
- Cell Proliferation
- Localization
- Cell Growth
- Secretion
- Dna Hypermethylation
- Inflammatory Response
PTMs
- Methylation
- Phosphorylation
- Acetylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Gnmt
bosterbio.com/bosterbio-gene-info-cards/Gnmt
References
PMID: 9497905 by Aida K., et al. Mouse glycine N-methyltransferase is sexually dimorphic and regulated by growth hormone.
PMID: 15340920 by Pakhomova S., et al. Glycine N-methyltransferases: a comparison of the crystal structures and kinetic properties of recombinant human, mouse and rat enzymes.