OVOL2 Antibodies

AND OVOL2 ELISA kits, OVOL2 Proteins

Many biological assays use antibodies to detect OVOL2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with OVOL2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop OVOL2 antibodies...

We validate the specificity of these antibodies to OVOL2 by testing them on tissues known to express OVOL2 positively and negatively. Browse below to find the OVOL2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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OVOL2 Infographic by Boster Bio

All OVOL2 Products

Product

Figures

Specificity

Applications

Price

Anti-OVOL2 Antibody

Human, Mouse

ELISA, WB

$380
Cat # A07631
100ul

OVOL2 (NM_021220) Human Over-expression Lysate

Human

$628
Cat # LS058495
100 µg

Anti-OVOL2 Antibody Picoband™

Human

ELISA, Flow Cytometry, IF, ICC, WB

$370
Cat # A07631-2
100 µg/vial

OVOL2 Overview

Facts about Transcription factor Ovo-like 2.

OVOL2 3D structure. Source: alphafold

Transcription factor Ovo-like 2 (OVOL2)

Zinc-finger transcription repressor factor (PubMed:19700410). Plays a crucial role in keeping the identity of epithelial lineages by suppressing epithelial-to mesenchymal transition (EMT) mainly through the repression of ZEB1, an EMT inducer (By similarity).

Positively regulates neuronal differentiation (By similarity). Suppresses cell cycling and terminal differentiation of keratinocytes by directly repressing MYC and NOTCH1 (PubMed:19700410).

Gene Information

Human
Gene Name:	OVOL2
Uniprot:	Q9BRP0
Entrez:	58495

Family

Belongs to:

krueppel C2H2-type zinc-finger protein family

Alternative Names

bA504H3.3; hOvo2; ovo-like 2 (Drosophila); transcription factor Ovo-like 2; Zinc finger protein 339EUROIMAGE566589; ZNF339

Molecular Weight

Mass (kDA):
30.438 kDA

Genomic Context


Human

Location:	20p11.23
Sequence:	20; NC_000020.11 (18024152..18059188, complement)

Tissue Specificity

Expressed in testis, ovary, heart and skeletal muscle (PubMed:12213202). Expressed in the cornea, but absent from the corneal endothelium (PubMed:26749309).

Subcellular Localizations

Nucleus.

Diseases

Corneal Edema
Infertility
Fetal Death
Glaucoma
Cystic Kidney Diseases
Crest Syndrome
Hereditary Corneal Dystrophy
Dystrophy
Blind Vision

Edema
Tumor Angiogenesis
Polymorphous Corneal Dystrophy
Pathologic Neovascularization

Pathways

Spermatogenesis
Tube Development
Heart Formation
Cell Cycle
Angiogenesis
Pachytene

Neural Tube Development

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/OVOL2

References

PMID: 12213202 by Li B., et al. Ovol2, a mammalian homolog of Drosophila ovo: gene structure, chromosomal mapping, and aberrant expression in blind-sterile mice.

PMID: 19700410 by Wells J., et al. Ovol2 suppresses cell cycling and terminal differentiation of keratinocytes by directly repressing c-Myc and Notch1.