Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform (PPP2R2B)

The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. Within the PP2A holoenzyme complex, isoform 2 is needed to promote proapoptotic activity (By similarity).

Isoform 2 regulates neuronal survival through the mitochondrial fission and fusion balance (By similarity). .