PUS7 Antibodies

AND PUS7 ELISA kits, PUS7 Proteins

Many biological assays use antibodies to detect PUS7, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PUS7 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PUS7 antibodies...

We validate the specificity of these antibodies to PUS7 by testing them on tissues known to express PUS7 positively and negatively. Browse below to find the PUS7 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PUS7 Infographic by Boster Bio

All PUS7 Products

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Applications

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Anti-PUS7 Mouse Monoclonal Antibody [Clone ID: OTI4C6]

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PUS7 (Right lane) cDNA for 48 hrs and lysed

Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-PUS7 monoclonal antibody

Dog, Human, Monkey, Mouse, Rat

Flow Cytometry, IF, WB

$523
Cat # M13434
100 µl

PUS7 (NM_019042) Human Over-expression Lysate

Human

$628
Cat # LS054517
20 µg, 100 µg

Anti-PUS7 Antibody Picoband®

Western blot analysis of PUS7 using anti-PUS7 antibody (A13434-1)

IHC analysis of PUS7 using anti-PUS7 antibody (A13434-1)

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A13434-1
100 µg/vial

PUS7 Overview

Facts about Pseudouridylate synthase 7 homolog.

Pseudouridylate synthase 7 homolog (PUS7)

Pseudouridylate synthase that catalyzes pseudouridylation of RNAs (PubMed:28073919, PubMed:29628141). Acts as a regulator of protein synthesis in embryonic stem cells by mediating pseudouridylation of RNA fragments derived from tRNAs (tRFs): pseudouridylated tRFs inhibit translation by targeting the translation initiation complex (PubMed:29628141).

Also catalyzes pseudouridylation of mRNAs: mediates pseudouridylation of mRNAs with the consensus sequence 5'-UGUAG-3' (PubMed:28073919). Besides mRNAs and tRNAs, binds other types of RNAs, like snRNAs, Y RNAs and vault RNAs, suggesting that it can catalyze pseudouridylation of several RNA types (PubMed:29628141).

Gene Information

Human
Gene Name:	PUS7
Uniprot:	Q96PZ0
Entrez:	54517

Family

Belongs to:

pseudouridine synthase TruD family

Alternative Names

EC 5.4.99.-; FLJ20485; KIAA1897; MGC17720; pseudouridylate synthase 7 homolog (S. cerevisiae); pseudouridylate synthase 7 homolog

Molecular Weight

Mass (kDA):
75.035 kDA

Genomic Context


Human

Location:	7q22.3
Sequence:	7; NC_000007.14 (105456501..105522271, complement)

Subcellular Localizations

Nucleus.

Pathways

Rna Modification

PTMs

Acetylation

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PUS7

References

PMID: 28073919 by Safra M., et al. TRUB1 is the predominant pseudouridine synthase acting on mammalian mRNA via a predictable and conserved code.

PMID: 29628141 by Guzzi N., et al. Pseudouridylation of tRNA-derived fragments steers translational control in stem cells.