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Receptor for BTLA.Receptor for TNFSF14/LIGHT and homotrimeric TNFSF1/lymphotoxin-alpha.
Involved in lymphocyte activation. Plays an important role in HSV pathogenesis because it enhanced the entry of numerous wild-type HSV strains of both serotypes to CHO cells, and mediated HSV entry into activated human T-cells.
|tumor necrosis factor receptor superfamily|
|Sequence:||1; NC_000001.11 (2556365..2565622)|
Widely expressed, with the highest expression in lung, spleen and thymus.
Cell membrane; Single-pass type I membrane protein.