Transformer-2 protein homolog beta (TRA2B)

Sequence-specific RNA-binding protein that participates in the control of pre-mRNA splicing. Acts additively with RBMX to promote exon 7 inclusion of the survival motor neuron SMN2.

Activates the splicing of MAPT/Tau exon 10. Alters pre-mRNA splicing patterns by antagonizing the effects of splicing regulators, like RBMX.