Anti-BNIP3 Antibody Picoband™

BNIP3 antibody

Boster Bio Anti-BNIP3 Antibody Picoband™ catalog # A01469. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. Cited in 2 publication(s).

Product Info Summary

SKU: A01469
Size: 100 μg/vial
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: WB

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Product Name

Anti-BNIP3 Antibody Picoband™

View all BNIP3 Antibodies

SKU/Catalog Number

A01469

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-BNIP3 Antibody Picoband™ catalog # A01469. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-BNIP3 Antibody Picoband™ (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01469)

Host

Rabbit

Contents

Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human BNIP3, identical to the related mouse and rat sequences.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins.

Reactive Species

A01469 is reactive to BNIP3 in Human, Mouse, Rat

Applications

A01469 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

21 kDa

Calculated molecular weight

27.832kDa

Background of BNIP3

The Bcl-2 nineteen kilodalton interacting protein 3 (BNIP3 or NIP3), is a hypoxia-inducible proapoptotic member of the Bcl-2 family that induces cell death by associating with the mitochondria. BNIP3, expressed in skeletal muscle and in the brain at low levels, is primarily localized to the nucleus of glial cells of the normal human brain, as well as in the malignant glioma cell line U251. BNIP3 expression in the cytoplasm increases and localizes with the mitochondria, contributing to induction of cell death. Cellular protein BNIP3 interacts with E1B-19K, BCL-2, BCL-xL, and EBV-BHRF1. BNIP3 contains Bcl-2 homology 3 (BH3) domain and COOH-terminal transmembrane (TM) domain. The BH3 domain of BNIP3 mediates Bcl-2/Bcl-X (L) heterodimerization and confers pro-apoptotic activity; whereas the TM domain is critical for homodimerization, pro-apoptotic function, and mitochondrial targeting.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml

Validation Images & Assay Conditions

Gene/Protein Information For BNIP3 (Source: Uniprot.org, NCBI)

Gene Name

BNIP3

Full Name

BCL2/adenovirus E1B 19 kDa protein-interacting protein 3

Weight

27.832kDa

Superfamily

NIP3 family

Alternative Names

BCL2/adenovirus E1B 19 kDa protein-interacting protein 3; BCL2/adenovirus E1B 19kDa interacting protein 3; BCL2/adenovirus E1B 19kD-interacting protein 3; BNIP3; Nip3 BNIP3 NIP3 BCL2 interacting protein 3 BCL2/adenovirus E1B 19 kDa protein-interacting protein 3|BCL2/adenovirus E1B 19kDa interacting protein 3|BCL2/adenovirus E1B interacting protein 3|nineteen kD interacting protein-3

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on BNIP3, check out the BNIP3 Infographic

BNIP3 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for BNIP3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Hello CJ!

A01469 has been cited in 2 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

Zhao YC,Guo W,Gao BH. Hypoxic training upregulates mitochondrial turnover and angiogenesis of skeletal muscle in mice. Life Sci. 2021 Mar 11:119340.doi:10.1016/j.lfs.2021.119340.Epub ahead of print.PMID:33716067.
Species: Mouse
A01469 usage in article: APP:WB, SAMPLE:GASTROCNEMIUS TISSUE, DILUTION:1:1000

Du Y, Li J, Xu T, Zhou DD, Zhang L, Wang X. Oncotarget. 2017 Jun 22;8(37):61510-61527. doi: 10.18632/oncotarget.18604. eCollection 2017 Sep 22. MicroRNA-145 induces apoptosis of glioma cells by targeting BNIP3 and Notch signaling

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Order DetailsPrice
A01469

100μg

$370
A01469-10ug

10μg sample (liquid)

$99
A01469-Biotin

100 μg Biotin conjugated

$570
A01469-Cy3

100 μg Cy3 conjugated

$570
A01469-Dylight488

100 μg Dylight488 conjugated

$570
A01469-Dylight550

100 μg Dylight550 conjugated

$570
A01469-Dylight594

100 μg Dylight594 conjugated

$570
A01469-FITC

100 μg FITC conjugated

$570
A01469-HRP

100 μg HRP conjugated

$570
A01469-APC

100 μg APC conjugated

$670
A01469-PE

100 μg PE conjugated

$670
A01469-carrier-free

Carrier Free

$370

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A01469
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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