Anti-Cyclophilin F (Y121) PPIF Antibody

Cyclophilin-F antibody

Boster Bio Anti-Cyclophilin F (Y121) PPIF Antibody catalog # A02803Y121. Tested in WB,IHC applications. This antibody reacts with Human,Mouse,Rat.

Product Info Summary

SKU: A02803Y121
Size: 100ul
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: IHC, WB

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Product Name

Anti-Cyclophilin F (Y121) PPIF Antibody

View all Cyclophilin-F Antibodies

SKU/Catalog Number

A02803Y121

Size

100ul

Form

Liquid

Description

Boster Bio Anti-Cyclophilin F (Y121) PPIF Antibody catalog # A02803Y121. Tested in WB,IHC applications. This antibody reacts with Human,Mouse,Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Cyclophilin F (Y121) PPIF Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02803Y121)

Host

Rabbit

Contents

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from internal of human PPIF.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A02803Y121 is reactive to PPIF in Human, Mouse, Rat

Applications

A02803Y121 is guaranteed for IHC, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

22.04kDa

Background of Cyclophilin-F

PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Involved in regulation of the mitochondrial permeability transition pore (mPTP). It is proposed that its association with the mPTP is masking a binding site for inhibiting inorganic phosphate (Pi) and promotes the open probablity of the mPTP leading to apoptosis or necrosis; the requirement of the PPIase activity for this function is debated. In cooperation with mitochondrial TP53 is involved in activating oxidative stress-induced necrosis. Involved in modulation of mitochondrial membrane F1F0 ATP synthase activity and regulation of mitochondrial matrix adenine nucleotide levels. Has anti-apoptotic activity independently of mPTP and in cooperation with BCL2 inhibits cytochrome c-dependent apoptosis.

Bergsma D.J., J. Biol. Chem. 266:23204-23214(1991).
Deloukas P., Nature 429:375-381(2004).
The MGC Project Team, Genome Res. 14:2121-2127(2004).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:500-1:1000
IHC: 1:50-1:200

Validation Images & Assay Conditions

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Gene/Protein Information For PPIF (Source: Uniprot.org, NCBI)

Gene Name

PPIF

Full Name

Peptidyl-prolyl cis-trans isomerase F, mitochondrial

Weight

22.04kDa

Superfamily

cyclophilin-type PPIase family

Alternative Names

Cyclophilin F; CYP3FLJ90798; Cyp-D; hCyP3; MGC117207; mitochondrial; peptidyl-prolyl cis-trans isomerase, mitochondrial; peptidylprolyl isomerase F (cyclophilin F); peptidylprolyl isomerase F PPIF CYP3, CyP-M, Cyp-D, CypD peptidylprolyl isomerase F peptidyl-prolyl cis-trans isomerase F, mitochondrial|PPIase F|cyclophilin 3|cyclophilin D|cyclophilin F|mitochondrial cyclophilin|peptidyl-prolyl cis-trans isomerase, mitochondrial|rotamase F

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on PPIF, check out the PPIF Infographic

PPIF infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for PPIF: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A02803Y121-100ul

100ul

$405

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