Product Info Summary
| SKU: | M00597-1 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Mouse |
| Host: | Rat |
| Application: | Flow Cytometry, IP, IHC-F |
Product info
Product Name
Anti-Ms CD26 Purified Dpp4 Monoclonal Antibody
SKU/Catalog Number
M00597-1
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Ms CD26 Purified Dpp4 Monoclonal Antibody (Catalog# M00597-1). Tested in IP, Flow Cytometry, IHC-F application(s). This antibody reacts with Mouse.
Storage & Handling
Store at 2-8°C. Do not freeze.
Cite This Product
Anti-Ms CD26 Purified Dpp4 Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M00597-1)
Host
Rat
Contents
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Clonality
Monoclonal
Clone Number
H194-112
Isotype
Rat IgG2a kappa
Immunogen
BALB/c thymocytes. The rat monoclonal antibody H194-112 recognizes an extracellular epitope of CD26, a 110 kDa type II membrane glycoprotein, which is a peptidase expressed on mature thymocytes, T cells (especially activated), B cells, NK cells and macrophages.
Reactive Species
M00597-1 is reactive to DPP4 in Mouse
Observed Molecular Weight
19 kDa
Calculated molecular weight
87.4 kDa
Background of DPP4
CD26, also known as dipeptidyl peptidase IV (DPP-IV), is a homodimeric cell surface serine peptidase that degradates IFN-gamma-induced cytokines, acts as a T cell costimulatory molecule, and participates in multiple immunopathological roles in leukocyte homing and inflammation. Alterations in its peptidase activity are characteristic of malignant transformation. The enzymatic activity increases dramatically with tumour grade and severity. CD26 is expressed in various blood cell types, but also e.g. in cells that are histogenetically related to activated fibroblasts. Alterations in CD26 density have been reported on circulating monocytes and CD4+ T cells during rheumatoid arthritis and systemic lupus erythematosus.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
M00597-1 is guaranteed for Flow Cytometry, IP, IHC-F Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Flow cytometry: 1-4 μg/ml.
Validation Images & Assay Conditions
Click image to see more details
Separation of murine splenocytes stained using anti-mouse CD26 (H194-112) purified antibody (concentration in sample 4 µg/ml, DAR APC, red-filled) from murine splenocytes unstained by primary antibody (DAR APC, black-dashed) in flow cytometry analysis (surface staining).
Specific Publications For Anti-Ms CD26 Purified Dpp4 Monoclonal Antibody (M00597-1)
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