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Product Info Summary
| SKU: | A11802 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Chicken |
| Application: | ELISA, ICC, WB |
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Product info
Product Name
Anti-TCC52 DCAF12 Antibody
SKU/Catalog Number
A11802
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-TCC52 DCAF12 Antibody (Catalog # A11802). Tested in ELISA, WB, ICC applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
TCC52 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-TCC52 DCAF12 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A11802)
Host
Chicken
Contents
TCC52 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgY
Immunogen
TCC52 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human TCC52. The immunogen is located within amino acids 390 - 440 of TCC52.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A11802 is reactive to DCAF12 in Human, Mouse, Rat
Applications
A11802 is guaranteed for ELISA, ICC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
50.517kDa
Background of DCAF12
Cancer-testis (CT) antigens are a type of antigen whose expression is highly restricted, primarily in normal testis, but aberrantly in different tumor types. Their immunogenicity in cancer patients makes them prime targets for immunotherapy of human tumors. One such CT antigen is TCC52, a novel centrosomal protein. TCC52 is a WD repeat-containing protein that interacts with the COP9 signalosome, a macromolecular complex that interacts with cullin-RING E3 ligases and regulates their activity by hydrolyzing cullin-Nedd8 conjugates. The normal biological function of this protein is not known at this time.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
TCC52 antibody can be used for detection of TCC52 by Western blot at 1 μg/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μg/mL.
Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of TCC52 in 293 cell lysate with TCC52 antibody at 1 μg/mL.
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Immunocytochemistry of TCC52 in 293 cells with TCC52 antibody at 2.5 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For DCAF12 (Source: Uniprot.org, NCBI)
Gene Name
DCAF12
Full Name
DDB1- and CUL4-associated factor 12
Weight
50.517kDa
Superfamily
WD repeat DCAF12 family
Alternative Names
DDB1- and CUL4-associated factor 12; CT102; DDB1 and CUL4 associated factor 12; KIAA1892; TCC52; WDR40A DCAF12 CT102, KIAA1892, TCC52, WDR40A DDB1 and CUL4 associated factor 12 DDB1- and CUL4-associated factor 12|WD repeat domain 40A|WD repeat-containing protein 40A|cancer/testis antigen 102|centrosome-related protein TCC52|testis cancer centrosome-related protein
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on DCAF12, check out the DCAF12 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for DCAF12: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-TCC52 DCAF12 Antibody (A11802)
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No publications found for A11802
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