- Table of Content
Phosphorylation of WASF3 is critical for the stimulation of lamellipodia formation and cell migration. Involved in the regulation of cell adhesion and motility via phosphorylation of key regulators of these processes like BCAR1, CRK, CRKL, DOK1, EFS or NEDD9.
|protein kinase superfamily|
|Sequence:||9; NC_000009.12 (130713881..130887675)|
Cytoplasm, cytoskeleton. Nucleus. Mitochondrion. Shuttles between the nucleus and cytoplasm depending on environmental signals. Sequestered into the cytoplasm through interaction with 14-3-3 proteins. Localizes to mitochondria in response to oxidative stress (By similarity).; [Isoform IB]: Nucleus membrane; Lipid-anchor. The myristoylated c-ABL protein is reported to be nuclear.