ACOT4 Antibodies

AND ACOT4 ELISA kits, ACOT4 Proteins

Many biological assays use antibodies to detect ACOT4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ACOT4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ACOT4 antibodies...

We validate the specificity of these antibodies to ACOT4 by testing them on tissues known to express ACOT4 positively and negatively. Browse below to find the ACOT4 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ACOT4 Infographic by Boster Bio

All ACOT4 Products

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Specificity

Applications

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Anti-Acyl-coenzyme A thioesterase 4 ACOT4 Antibody

Immunohistochemistry validation of ACOT4 using Anti-Acyl-coenzyme A thioesterase 4 ACOT4 Antibody (A11674-1)

Human, Mouse

ELISA, IF, IHC, WB

$380
Cat # A11674-1
100ul

Acyl coenzyme A Thioesterase 4 (ACOT4) (NM_152331) Human Recombinant Protein

Coomassie blue staining of purified ACOT4 protein

$1062
Cat # PROTQ8N9L9
20 µg

Acyl coenzyme A Thioesterase 4 (ACOT4) (NM_152331) Human Over-expression Lysate

Human

$628
Cat # LS122970
20 µg, 100 µg

ACOT4 Overview

Facts about Peroxisomal succinyl-coenzyme A thioesterase.

ACOT4 3D structure. Source: alphafold

Peroxisomal succinyl-coenzyme A thioesterase (ACOT4)

Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH (By similarity). Succinyl-CoA thioesterase that also hydrolyzes long chain saturated and unsaturated monocarboxylic acyl-CoAs.

Gene Information

Human
Gene Name:	ACOT4
Uniprot:	Q8N9L9
Entrez:	122970

Family

Belongs to:

C/M/P thioester hydrolase family

Alternative Names

acyl-CoA thioesterase 4EC 3.1.2.2; acyl-coenzyme A thioesterase 4; Peroxisomal acyl coenzyme A thioester hydrolase Ib; peroxisomal acyl-CoA thioesterase 2B; Peroxisomal long-chain acyl-CoA thioesterase Ib; PTE-2b; PTE2BPTE1B; PTEIB; PTE-IbFLJ31235

Molecular Weight

Mass (kDA):
46.327 kDA

Genomic Context


Human

Location:	14q24.3
Sequence:	14; NC_000014.9 (73591706..73595766)

Tissue Specificity

Strongest expression in liver and kidney and weaker expression in placenta, heart, and muscle.

Subcellular Localizations

Peroxisome.

PTMs

Amidation

Oxidation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ACOT4

References

PMID: 16940157 by Hunt M.C., et al. Analysis of the mouse and human acyl-CoA thioesterase (ACOT) gene clusters shows that convergent, functional evolution results in a reduced number of human peroxisomal ACOTs.