All-trans-retinol dehydrogenase [NAD(+)] ADH7 (ADH7)

Could function in retinol oxidation for the synthesis of retinoic acid, a hormone essential for cellular differentiation. Medium-chain (octanol) and aromatic (m-nitrobenzaldehyde) chemicals are the best substrates.

Ethanol is not a good substrate but at the high ethanol concentrations attained in the digestive tract, it plays a role in the ethanol oxidation and contributes to the very first pass ethanol metabolism. .