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- Table of Contents
Designing an IHC experiment for ADM? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the ADM IHC GuideFacts about ADM.
In the kidney, am is diuretic and natriuretic, and both am and pamp inhibit aldosterone secretion by direct adrenal actions. In pituitary gland, both peptides at physiologically relevant doses inhibit basal ACTH secretion.
| Human | |
|---|---|
| Gene Name: | ADM |
| Uniprot: | P35318 |
| Entrez: | 133 |

| Belongs to: |
|---|
| adrenomedullin family |

ADM; Adrenomedullin; AMpreproadrenomedullin
Mass (kDA):
20.42 kDA

| Human | |
|---|---|
| Location: | 11p15.4 |
| Sequence: | 11; NC_000011.10 (10305073..10307397) |
Highest levels found in pheochromocytoma and adrenal medulla. Also found in lung, ventricle and kidney tissues.
Secreted.




PMID: 7688224 by Kitamura K., et al. Cloning and characterization of cDNA encoding a precursor for human adrenomedullin.
PMID: 8074714 by Ishimitsu T., et al. Genomic structure of human adrenomedullin gene.
*Showing only the more recent 20. More publications can be found for each product on its corresponding product page