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- Table of Contents
Apolipoprotein C-III Antibodies
AND APOC3 ELISA kits, Apolipoprotein C-III Proteins
Many biological assays use antibodies to detect Apolipoprotein C-III, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Apolipoprotein C-III in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Apolipoprotein C-III antibodies...
Designing an IHC experiment for Apolipoprotein C-III? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the APOC3 IHC GuideAPOC3 Infographic by Boster Bio
All APOC3 Products
Product
Figures
Specificity
Applications
Price
Human
$628
Cat # LS000345
20 µg, 100 µg
Cat # LS000345
20 µg, 100 µg
APOC3 Overview
Facts about Apolipoprotein C-III.
Apolipoprotein C-III (APOC3)
Component of triglyceride-rich very low density lipoproteins (VLDL) and high density lipoproteins (HDL) in plasma (PubMed:18201179, PubMed:22510806). Plays a multifaceted role in triglyceride homeostasis (PubMed:18201179, PubMed:22510806).
Intracellularly, promotes hepatic very low density lipoprotein 1 (VLDL1) secretion and assembly; extracellularly, attenuates hydrolysis and clearance of triglyceride-rich lipoproteins (TRLs) (PubMed:18201179, PubMed:22510806). Impairs the lipolysis of TRLs by inhibiting lipoprotein lipase and the hepatic uptake of TRLs by remnant receptors (PubMed:18201179, PubMed:22510806).
Gene Information
| Human | |
|---|---|
| Gene Name: | APOC3 |
| Uniprot: | P02656 |
| Entrez: | 345 |
Family
| Belongs to: |
|---|
| apolipoprotein C3 family |
Alternative Names
APOC3; APOCIII; apo-CIII; apoC-III; Apolipoprotein C3; apolipoprotein C-III; MGC150353
Molecular Weight
Mass (kDA):
10.852 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 11q23.3 |
| Sequence: | 11; NC_000011.10 (116829907..116833072) |
Tissue Specificity
Liver.
Subcellular Localizations
Secreted.
Diseases
- Diabetes Mellitus
- Cardiovascular Diseases
- Coronary Heart Disease
- Diabetes Mellitus, Non-insulin-dependent
- Obesity
- Heart Diseases
- Dysequilibrium Syndrome
- Dyslipidemias
- Insulin Resistance
- Coronary Artery Disease
- Atherosclerosis
- Hyperlipidemia
- Liver Diseases
Pathways
- Secretion
- Pathogenesis
- Transport
- Lipid Transport
- Platelet Aggregation
- Flight
- Lipid Homeostasis
- Localization
- Glucose Homeostasis
- Cholesterol Efflux
- Lipid Binding
- Cognition
- Aging
PTMs
- Phosphorylation
- Cleavage
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/APOC3
bosterbio.com/bosterbio-gene-info-cards/APOC3
References
PMID: 6439535 by Protter A.A., et al. Isolation and sequence analysis of the human apolipoprotein CIII gene and the intergenic region between the apo AI and apo CIII genes.
PMID: 6548954 by Levy-Wilson B., et al. Isolation and DNA sequence of full-length cDNA for human preapolipoprotein CIII.