ARFGAP1 Antibodies

AND ARFGAP1 ELISA kits, ARFGAP1 Proteins

Many biological assays use antibodies to detect ARFGAP1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ARFGAP1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ARFGAP1 antibodies...

We validate the specificity of these antibodies to ARFGAP1 by testing them on tissues known to express ARFGAP1 positively and negatively. Browse below to find the ARFGAP1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for ARFGAP1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the ARFGAP1 Western Blot Guide

ARFGAP1 Infographic by Boster Bio

All ARFGAP1 Products

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Anti-ARFGAP1 Antibody Picoband®

Western blot analysis of ARFGAP1 using anti-ARFGAP1 antibody (A04959)

IHC analysis of ARFGAP1 using anti-ARFGAP1 antibody (A04959)

Human, Mouse, Rat

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A04959
100 μg/vial

ARFGAP1 (NM_018209) Human Over-expression Lysate

ARFGAP1 Human Over-expression Lysates NM_018209

Human

$628
Cat # LS055738
20 µg, 100 µg

ARFGAP1 Overview

Facts about ADP-ribosylation factor GTPase-activating protein 1.

ARFGAP1 3D structure. Source: alphafold

ADP-ribosylation factor GTPase-activating protein 1 (ARFGAP1)

GTPase-activating protein (GAP) for the ADP ribosylation factor 1 (ARF1). Involved in membrane trafficking and /or vesicle transport.

Promotes hydrolysis of the ARF1-bound GTP and so, is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles, a necessity for vesicle's combination with target compartment. Probably regulates ARF1-mediated transportation via its interaction with the KDELR proteins and TMED2.

Gene Information

Human
Gene Name:	ARFGAP1
Uniprot:	Q8N6T3
Entrez:	55738

Family

Belongs to:

No superfamily

Alternative Names

ADP-ribosylation factor 1 GTPase activating protein; ADP-ribosylation factor 1 GTPase-activating protein; ADP-ribosylation factor GTPase activating protein 1; ADP-ribosylation factor GTPase-activating protein 1; ARF GAP 1; ARF1 GAP; ARF1-directed GTPase-activating protein; ARF1GAP; bA261N11.3; FLJ10767; GAP protein; HRIHFB2281; MGC39924

Molecular Weight

Mass (kDA):
44.668 kDA

Genomic Context


Human

Location:	20q13.33
Sequence:	20; NC_000020.11 (63272785..63289790)

Subcellular Localizations

Cytoplasm. Golgi apparatus. Associates with the Golgi complex.

Diseases

Autoimmune Lymphoproliferative Syndrome
Malignant Neoplasms
Tissue Adhesions
Parkinson Disease
Sclerosis
Melanoma
Malignant Neoplasm Of Breast
Speech Delay
Neoplasms
Behavioral Symptoms
Osteoporosis
Colorectal Cancer

Impaired Glucose Tolerance
Speech Disorders
Bulla
Cell Invasion
Neuroblastoma
Hereditary Diseases

Interacting Proteins

GABARAPL2
GRN
KRTAP10-9
KRTAP3-2
KRTAP9-2

LRRK2
TRIM23

Pathways

Transport
Localization
Secretory Pathway
Golgi Localization
Cell Migration
Endocytosis
Vesicle Uncoating
Membrane Fission
Rna Interference
Intracellular Transport
Actin Cytoskeleton Reorganization
Proteolysis
Hypersensitivity

Protein Adp-ribosylation
Regeneration
Phagocytosis
Cell Motility
Cell Death
Locomotion
Lipid Binding

PTMs

Ribosylation

Phosphorylation

Reduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ARFGAP1

References

PMID: 14702039 by Ota T., et al. Complete sequencing and characterization of 21,243 full-length human cDNAs.

PMID: 11780052 by Deloukas P., et al. The DNA sequence and comparative analysis of human chromosome 20.