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- Table of Contents
ASS1 Antibodies
AND ASS1 ELISA kits, ASS1 Proteins
Many biological assays use antibodies to detect ASS1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ASS1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ASS1 antibodies...
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ASS1 Infographic by Boster Bio
All ASS1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A02212-1
100 μg/vial
Cat # A02212-1
100 μg/vial
Human, Monkey, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M02212-1
100 μg/vial
Cat # M02212-1
100 μg/vial
Human, Monkey, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M02212-2
100 μg/vial
Cat # M02212-2
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M02212-3
100 μl/vial
Cat # M02212-3
100 μl/vial
ASS1 Overview
Facts about Argininosuccinate synthase.
Argininosuccinate synthase (ASS1)
One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism to inocuous urea in the liver of ureotelic animals. Catalyzes the formation of arginosuccinate from aspartate, citrulline and ATP and collectively with ASL it is responsible for the biosynthesis of arginine in most body tissues.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | ASS1 |
| Uniprot: | P00966 |
| Entrez: | 445 |
Family
| Belongs to: |
|---|
| argininosuccinate synthase family |
Alternative Names
argininosuccinate synthase 1; argininosuccinate synthase; argininosuccinate synthetase 1; argininosuccinate synthetase; ASSCTLN1; citrulline-aspartate ligase; Citrulline--aspartate ligase; EC 6.3.4.5
Molecular Weight
Mass (kDA):
46.53 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 9q34.11 |
| Sequence: | 9; NC_000009.12 (130444707..130501274) |
Tissue Specificity
Expressed in adult liver.
Subcellular Localizations
Cytoplasm, cytosol.
Diseases
- Citrullinemia
- Malignant Neoplasms
- Hyperammonemia
- Leukemia
- Neoplasms
- Malignant Paraganglionic Neoplasm
- Tissue Adhesions
- Encephalopathies
- Pleural Mesothelioma
- Myeloid Leukemia
- Urea Cycle Disorders, Inborn
- Brain Injuries
- Cleft Palate
Interacting Proteins
- ARAF
- NMRAL1
Pathways
- Urea Cycle
- Methylation
- Pathogenesis
- Rna Interference
- Cell Adhesion
- Cell Migration
- Gene Silencing
- Conjugation
- Drug Resistance
- Translation
PTMs
- Oxidation
- Methylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ASS1
bosterbio.com/bosterbio-gene-info-cards/ASS1
References
PMID: 6194510 by Bock H.-G.O., et al. Sequence for human argininosuccinate synthetase cDNA.
PMID: 6321498 by Freytag S.O., et al. Molecular structures of human argininosuccinate synthetase pseudogenes. Evolutionary and mechanistic implications.