Cysteine protease ATG4D Antibodies

AND ATG4D ELISA kits, Cysteine protease ATG4D Proteins

Many biological assays use antibodies to detect Cysteine protease ATG4D, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Cysteine protease ATG4D in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Cysteine protease ATG4D antibodies...

We validate the specificity of these antibodies to Cysteine protease ATG4D by testing them on tissues known to express ATG4D positively and negatively. Browse below to find the ATG4D antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ATG4D Infographic by Boster Bio

All ATG4D Products

Product

Figures

Specificity

Applications

Price

Anti-Cysteine protease ATG4D ATG4D Antibody

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$449
Cat # A09793
0.1 mg

Anti-ATG4D Antibody

Human

IF, WB

$298
Cat # M09793
80 µl

ATG4D Overview

Facts about Cysteine protease ATG4D.

ATG4D 3D structure. Source: alphafold

Cysteine protease ATG4D (ATG4D)

Cysteine protease ATG4D: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine.

Exposure of the glycine in the C-terminus is vital for ATG8 proteins conjugation into phosphatidylethanolamine (PE) and insertion to membranes, which is essential for autophagy. Has also an activity of delipidating receptor to the PE-conjugated forms.

Gene Information

Human
Gene Name:	ATG4D
Uniprot:	Q86TL0
Entrez:	84971

Family

Belongs to:

peptidase C54 family

Alternative Names

APG4 autophagy 4 homolog D (S. cerevisiae); APG4 autophagy 4 homolog D; APG4D; APG4-D; ATG4 autophagy related 4 homolog D (S. cerevisiae); AUTL4; AUT-like 4 cysteine endopeptidase; AUT-like 4, cysteine endopeptidase (S. cerevisiae); AUT-like 4, cysteine endopeptidase; autophagin-4; Autophagy-related cysteine endopeptidase 4; Autophagy-related protein 4 homolog D; cysteine protease ATG4D; cysteine protease involved in autophagy; EC 3.4.22; EC 3.4.22.-

Molecular Weight

Mass (kDA):
52.922 kDA

Genomic Context


Human

Location:	19p13.2
Sequence:	19; NC_000019.10 (10543897..10553418)

Tissue Specificity

Mainly expressed in skeletal muscle and, to a lower extent, in testis.

Subcellular Localizations

[Cysteine protease ATG4D]: Cytoplasm.; [Cysteine protease ATG4D, mitochondrial]: Cytoplasm. Mitochondrion matrix. Imported into mitochondrial matrix after cleavage by CASP3 during oxidative stress and cell death.