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- Table of Contents
C-C motif chemokine 2 Antibodies
AND CCL2 ELISA kits, C-C motif chemokine 2 Proteins
Many biological assays use antibodies to detect C-C motif chemokine 2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with C-C motif chemokine 2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop C-C motif chemokine 2 antibodies...
Designing a Western blot for C-C motif chemokine 2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the CCL2 Western Blot GuideCCL2 Infographic by Boster Bio
All CCL2 Products
Product
Figures
Specificity
Applications
Price
Human
ELISA
$399
Cat # EK0441
96 wells/kit, with removable strips.
Cat # EK0441
96 wells/kit, with removable strips.
Rat MCP-1 ELISA Kit PicoKine®
37 Citations
Rat
ELISA
$499
Cat # EK0902
96 wells/kit, with removable strips.
Cat # EK0902
96 wells/kit, with removable strips.
Human
ELISA
$499
Cat # EK0453
96 wells/kit, with removable strips.
Cat # EK0453
96 wells/kit, with removable strips.
Mouse
ELISA
$499
Cat # EK0447
96 wells/kit, with removable strips.
Cat # EK0447
96 wells/kit, with removable strips.
Human
ELISA
$499
Cat # EK0446
96 wells/kit, with removable strips.
Cat # EK0446
96 wells/kit, with removable strips.
Human
ELISA
$500
Cat # EZ0441
For 5 plates, 96 wells each
Cat # EZ0441
For 5 plates, 96 wells each
Human
ELISA
$499
Cat # EK0555
96 wells/kit, with removable strips.
Cat # EK0555
96 wells/kit, with removable strips.
Mouse CCL21/6Ckine/Ccl21a ELISA Kit PicoKine®
3 Citations
Mouse
ELISA
$499
Cat # EK0556
96 wells/kit, with removable strips.
Cat # EK0556
96 wells/kit, with removable strips.
Human CCL23/MPIF-1 ELISA Kit PicoKine®
1 Citations
Human
ELISA
$499
Cat # EK1224
96 wells/kit, with removable strips.
Cat # EK1224
96 wells/kit, with removable strips.
Human
ELISA
$499
Cat # EK0688
96 wells/kit, with removable strips.
Cat # EK0688
96 wells/kit, with removable strips.
Human
ELISA
$499
Cat # EK0331
96 wells/kit, with removable strips.
Cat # EK0331
96 wells/kit, with removable strips.
Human
ELISA
$500
Cat # EZ0555
For 5 plates, 96 wells each
Cat # EZ0555
For 5 plates, 96 wells each
Human
ELISA
$500
Cat # EZ0331
5 plates/kit
Cat # EZ0331
5 plates/kit
Mouse CCL25/TECK PicoKine® Quick ELISA Kit
1 Citations
Mouse
ELISA
$499
Cat # FEK1424
96 wells/kit, with removable strips.
Cat # FEK1424
96 wells/kit, with removable strips.
Mouse CCL25/TECK ELISA Kit PicoKine®
1 Citations
Mouse
ELISA
$499
Cat # EK1424
96 wells/kit, with removable strips.
Cat # EK1424
96 wells/kit, with removable strips.
Human
ELISA
$499
Cat # FEK0441
96 wells/kit, with removable strips.
Cat # FEK0441
96 wells/kit, with removable strips.
Human
ELISA
$499
Cat # FEK1224
96 wells/kit, with removable strips.
Cat # FEK1224
96 wells/kit, with removable strips.
Human
ELISA
$499
Cat # FEK1145
96 wells/kit, with removable strips.
Cat # FEK1145
96 wells/kit, with removable strips.
Human
ELISA
$499
Cat # FEK0555
96 wells/kit, with removable strips.
Cat # FEK0555
96 wells/kit, with removable strips.
Human
ELISA
$499
Cat # FEK0446
96 wells/kit, with removable strips.
Cat # FEK0446
96 wells/kit, with removable strips.
Human
ELISA
$499
Cat # FEK0331
96 wells/kit, with removable strips.
Cat # FEK0331
96 wells/kit, with removable strips.
Human
ELISA
$499
Cat # EK1145
96wells/kit, with removable strips.
Cat # EK1145
96wells/kit, with removable strips.
Human
ELISA
$499
Cat # EK0687
96 wells/kit, with removable strips.
Cat # EK0687
96 wells/kit, with removable strips.
Mouse
ELISA
$500
Cat # EZ0454
For 5 plates, 96 wells each
Cat # EZ0454
For 5 plates, 96 wells each
Mouse
ELISA
$499
Cat # FEK0568
96 wells/kit, with removable strips.
Cat # FEK0568
96 wells/kit, with removable strips.
Mouse
ELISA
$499
Cat # FEK0576
96 wells/kit, with removable strips.
Cat # FEK0576
96 wells/kit, with removable strips.
Mouse
ELISA
$499
Cat # EK0689
96 wells/kit, with removable strips.
Cat # EK0689
96 wells/kit, with removable strips.
Mouse
ELISA
$499
Cat # EK0576
96 wells/kit, with removable strips.
Cat # EK0576
96 wells/kit, with removable strips.
Mouse
ELISA
$499
Cat # EK0454
96 wells/kit, with removable strips.
Cat # EK0454
96 wells/kit, with removable strips.
Rat
ELISA
$499
Cat # EK0455
96 wells/kit, with removable strips.
Cat # EK0455
96 wells/kit, with removable strips.
Canine
ELISA
$499
Cat # EK2331
96 wells/kit, with removable strips.
Cat # EK2331
96 wells/kit, with removable strips.
Anti-C-C motif chemokine 2 CCL2 Antibody
5 Citations
Human, Mouse, Rat
ELISA, IF, IHC-P, WB
$481
Cat # A00056
0.1 mg
Cat # A00056
0.1 mg
Human, Mouse, Rat
Flow Cytometry, IF, ICC, WB
$370
Cat # M05293
100 μl/vial
Cat # M05293
100 μl/vial
Human, Mouse
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00056-2
100 μg
Cat # M00056-2
100 μg
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00748
100 μg
Cat # M00748
100 μg
Human
$628
Cat # LS006368
20 µg, 100 µg
Cat # LS006368
20 µg, 100 µg
Human
$628
Cat # LS006364
20 µg, 100 µg
Cat # LS006364
20 µg, 100 µg
Swine
Cell Culture
$154
Cat # PROTP42831
5ug,20ug
Cat # PROTP42831
5ug,20ug
Human
Cell Culture
$77
Cat # PROTP13500-5
5ug,20ug,100ug
Cat # PROTP13500-5
5ug,20ug,100ug
Mouse
Cell Culture
$77
Cat # PROTP10148-4
5ug,20ug,100ug
Cat # PROTP10148-4
5ug,20ug,100ug
$1249
Cat # PROTP55773
20 µg
Cat # PROTP55773
20 µg
CCL2 Overview
Facts about C-C motif chemokine 2.
C-C motif chemokine 2 (CCL2)
Chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. Augments monocyte anti-tumor activity.
Has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis.
Gene Information
| Human | |
|---|---|
| Gene Name: | CCL2 |
| Uniprot: | P13500 |
| Entrez: | 6347 |
Family
| Belongs to: |
|---|
| intercrine beta (chemokine CC) family |
Alternative Names
C-C motif chemokine ligand 2; CCL2; GDCF-2; HC11; HSMCR30; MCAF; Mcp1; MCP-1; SCYA2; SMC-CF
Molecular Weight
Mass (kDA):
11.025 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 17q12 |
| Sequence: | 17; NC_000017.11 (34255285..34257203) |
Tissue Specificity
Expressed in the seminal plasma, endometrial fluid and follicular fluid (at protein level).
Subcellular Localizations
Secreted.
Diseases
- Inflammation
- Tissue Adhesions
- Atherosclerosis
- Inflammatory Response
- Cholangiocarcinoma
- Neoplasms
- Fibrosis
- Malignant Neoplasms
- Diabetes Mellitus
- Kidney Diseases
- Obesity
- Nervousness
- Autoimmune Reaction
Interacting Proteins
- CCL5
- CCL8
- PF4
- TNFAIP6
Pathways
- Pathogenesis
- Secretion
- Inflammatory Response
- Chemotaxis
- Immune Response
- Angiogenesis
- Cell Adhesion
- Chemokine Production
- Cytokine Production
- Cell Migration
- Cell Proliferation
- Cell Death
- Cell Activation
PTMs
- Phosphorylation
- Cleavage
- Oxidation
- Reduction
- Acetylation
- Methylation
- Biotinylation
- Glycosylation
- Demethylation
- Nitration
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CCL2
bosterbio.com/bosterbio-gene-info-cards/CCL2
References
PMID: 2923622 by Furutani Y., et al. Cloning and sequencing of the cDNA for human monocyte chemotactic and activating factor (MCAF).
PMID: 2513477 by Rollins B.J., et al. The human homolog of the JE gene encodes a monocyte secretory protein.
218 Publications of Boster C-C motif chemokine 2 Antibodies & ELISA Kits
- PubMed ID: PMID:31966515, Identification of genes involved in enterovirus 71 infected SK-N-SH cells
- PubMed ID: PMID:31105824, Vaccarin prevents ox-LDL-induced HUVEC EndMT, inflammation and apoptosis by supp...
- PubMed ID: PMID:26221302, Comparison of biomarkers in rat renal ischemia-reperfusion injury
- PubMed ID: PMID:25683933, Comparative analysis of MCP-1 and TF in elderly patients with acute exacerbation...
- PubMed ID: 10.7150/ijbs.25349, CCL2-SQSTM1 positive feedback loop suppresses autophagy to promote chemoresistan...
- PubMed ID: 10.5551/jat.24372, Involvement of TLR4 in Oxidized LDL/β2GPI/Anti-β2GPI-Induced Transformation of...
- PubMed ID: 10.4049/jimmunol.1900083, USP19 Inhibits TNF-α– and IL-1β–Triggered NF-κB Activation by Deubiquitin...
- PubMed ID: 10.3892/ol.2012.1047, Endogenous PGE2 induces MCP‑1 expression via EP4/p38 MAPK signaling in melano...
- PubMed ID: 10.3892/mmr.2019.10407, Tanshinone IIA attenuates cerebral aneurysm formation by inhibiting the NF‑κB...
- PubMed ID: 10.3892/ijmm.2014.1844, A potential therapeutic effect of CYP2C8 overexpression on anti-TNF-α activity
- PubMed ID: 10.3892/etm.2018.6995, Thalidomide decreases high glucose‑induced extracellular matrix protein synthe...
- PubMed ID: 10.3892/etm.2017.4845, Effects of leukotriene B4 on interleukin-32, interferon-γ and chemokines in rat...
- PubMed ID: 10.3390/nu7085324, Apple Polyphenols Decrease Atherosclerosis and Hepatic Steatosis in ApoE−/− ...
- PubMed ID: 10.3390/nu11122855, The Extra-Virgin Olive Oil Polyphenols Oleocanthal and Oleacein Counteract Infla...
- PubMed ID: 10.3390/molecules190812827, Anti-Inflammatory Effect of the Blueberry Anthocyanins Malvidin-3-Glucoside and ...
- PubMed ID: 10.3390/ijms21041240, Downregulation of S1P Lyase Improves Barrier Function in Human Cerebral Microvas...
- PubMed ID: 10.3390/ijms20184389, Effect of Tff3 Deficiency and ER Stress in the Liver
- PubMed ID: 10.3390/ijms19051498, Downregulation of the S1P Transporter Spinster Homology Protein 2 (Spns2) Exerts...
- PubMed ID: 10.3390/ijms18040844, Hypaphorine Attenuates Lipopolysaccharide-Induced Endothelial Inflammation via R...
- PubMed ID: 10.3390/genes11111309, Lymphatic Metastasis of NSCLC Involves Chemotaxis Effects of Lymphatic Endotheli...
- PubMed ID: 10.3389/fphar.2019.01432, The Potassium SK Channel Activator NS309 Protects Against Experimental Traumatic...
*Showing only the more recent 20. More publications can be found for each product on its corresponding product page