Protein Dr1 (DR1)

The institution of this DR1/DRAP1 heterodimer with TBP leads to a functional repression of both activated and basal transcription of class II genes. This interaction precludes the creation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP.

Can bind to DNA by itself. Part of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4.