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Regulates the vascular endothelial growth factor (VEGF) expression and appears to be implicated in the development of blood vessels and the tubular system of lung. May also play a role in the formation of the endothelium that gives rise to the blood brain barrier.
|Sequence:||2; NC_000002.12 (46297407..46386697)|
Expressed in most tissues, with highest levels in placenta, lung and heart. Selectively expressed in endothelial cells.
Nucleus. Nucleus speckle. Colocalizes with HIF3A in the nucleus and speckles.
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