Chimeric ERCC6-PGBD3 protein (ERCC6)

Involved in repair of DNA damage after UV irradiation, acting in the absence of ERCC6 or synergistically with ERCC6. Involved in the regulation of gene expression.

In the absence of ERCC6, induces the expression of genes characteristic of interferon-like antiviral responses. This response is almost completely suppressed in the presence of ERCC6.