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- Table of Contents
Designing a Western blot for FMO3? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the FMO3 Western Blot GuideFacts about Dimethylaniline monooxygenase [N-oxide-forming] 3.
Plays an important role in the metabolism of trimethylamine (TMA), via the production of TMA N-oxide (TMAO). Is also able to perform S-oxidation when acting on sulfide compounds (PubMed:9224773).
| Human | |
|---|---|
| Gene Name: | FMO3 |
| Uniprot: | P31513 |
| Entrez: | 2328 |

| Belongs to: |
|---|
| FMO family |

dimethylaniline monooxygenase [N-oxide-forming] 3; Dimethylaniline oxidase 3; dJ127D3.1; EC 1.14.13.8; flavin containing monooxygenase 3; FMO 3; FMO form 2; FMO II; FMOII; Hepatic flavin-containing monooxygenase 3; hepatic flavin-containing monooxygenase-3; MGC34400; TMAU
Mass (kDA):
60.033 kDA

| Human | |
|---|---|
| Location: | 1q24.3 |
| Sequence: | 1; NC_000001.11 (171090873..171117819) |
Liver.
Microsome membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein.




PMID: 1542660 by Lomri N., et al. Molecular cloning of the flavin-containing monooxygenase (form II) cDNA from adult human liver.
PMID: 8654418 by Dolphin C.T., et al. Differential developmental and tissue-specific regulation of expression of the genes encoding three members of the flavin- containing monooxygenase family of man, FMO1, FMO3 and FM04.