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Forkhead box protein E1 Antibodies
AND FOXE1 ELISA kits, Forkhead box protein E1 Proteins
Many biological assays use antibodies to detect Forkhead box protein E1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Forkhead box protein E1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Forkhead box protein E1 antibodies...
Designing a Western blot for Forkhead box protein E1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the FOXE1 Western Blot GuideFOXE1 Infographic by Boster Bio
All FOXE1 Products
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FOXE1 Overview
Facts about Forkhead box protein E1.
Forkhead box protein E1 (FOXE1)
Transcription factor that binds consensus websites on many different gene promoters and activate their transcription. Involved in appropriate palate formation, most likely through the expression of MSX1 and TGFB3 genes which are direct targets of this transcription element.
Also implicated in thyroid gland morphogenesis. May indirectly play a role in cell growth and migration through the regulation of WNT5A expression.
Gene Information
| Human | |
|---|---|
| Gene Name: | FOXE1 |
| Uniprot: | O00358 |
| Entrez: | 2304 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
FKHL15HFKL5; forkhead box E1 (thyroid transcription factor 2); forkhead box E2; Forkhead box protein E2; forkhead, drosophila, homolog-like 15; Forkhead-related protein FKHL15; HFKH4Thyroid transcription factor 2; TITF2HNF-3/fork head-like protein 5; TTF2forkhead box protein E1; TTF-2FOXE2
Molecular Weight
Mass (kDA):
38.076 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 9q22.33 |
| Sequence: | 9; NC_000009.12 (97853226..97856717) |
Tissue Specificity
Detected in adult brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, heart, colon, small intestine testis and thymus. Expression was strongest in heart and pancreas.
Subcellular Localizations
Nucleus.
Diseases
- Hypothyroidism
- Congenital Abnormality
- Congenital Hypothyroidism
- Malignant Neoplasms
- Cleft Palate
- Carcinoma
- Neoplasms
- Malignant Neoplasm Of Thyroid
- Thyroid Neoplasm
- Congenital Absence
- Cleft Lip
- Choanal Atresia
Interacting Proteins
- ELK1
Pathways
- Methylation
- Pathogenesis
- Cell Differentiation
- Dna Methylation
- Tissue Homeostasis
- Transport
- Cell Cycle
- Gland Morphogenesis
- Localization
- Hair Follicle Morphogenesis
- Cell Proliferation
- Cell Growth
- Secretion
PTMs
- Methylation
- Demethylation
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FOXE1
bosterbio.com/bosterbio-gene-info-cards/FOXE1
References
PMID: 9052737 by Wiese S., et al. The novel human HNF-3/fork head-like 5 gene: chromosomal localization and expression pattern.
PMID: 9169137 by Chadwick B.P., et al. FKHL15, a new human member of the forkhead gene family located on chromosome 9q22.