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- Table of Contents
Fascin Antibodies
AND FSCN1 ELISA kits, Fascin Proteins
Many biological assays use antibodies to detect Fascin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Fascin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Fascin antibodies...
Designing a Western blot for Fascin? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the FSCN1 Western Blot GuideFSCN1 Infographic by Boster Bio
All FSCN1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M02147-1
100 μl
Cat # M02147-1
100 μl
FSCN1 Overview
Facts about Fascin.
Fascin (FSCN1)
Organizes filamentous actin into bundles with a minimum of 4.1:1 actin/fascin ratio.
Plays a role in the organization of actin filament bundles and the formation of microspikes, membrane ruffles, and stress fibers. Important for the creation of a diverse set of cell protrusions, such as filopodia, and for cell motility and migration.
Gene Information
| Human | |
|---|---|
| Gene Name: | FSCN1 |
| Uniprot: | Q16658 |
| Entrez: | 6624 |
Family
| Belongs to: |
|---|
| fascin family |
Alternative Names
FAN1; FAN1,55 kDa actin-bundling protein; fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus); Fascin; FLJ38511; FSCN1; HSN; p55actin bundling protein; singed (Drosophila)-like (sea urchin fascin homolog like); singed-like (fascin homolog, sea urchin); Singed-like Protein; SNL; SNLfascin
Molecular Weight
Mass (kDA):
54.53 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 7p22.1 |
| Sequence: | 7; NC_000007.14 (5592816..5606655) |
Tissue Specificity
Ubiquitous.
Subcellular Localizations
Cytoplasm, cytosol. Cytoplasm, cell cortex. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, stress fiber. Cell projection, filopodium. Cell projection, invadopodium. Cell projection, microvillus. Cell junction. Colocalized with RUFY3 and F-actin at filipodia of the axonal growth cone. Colocalized with DBN1 and F-actin at the transitional domain of the axonal growth cone (By similarity).
Diseases
- Neoplasms
- Malignant Neoplasms
- Carcinoma
- Cell Invasion
- Neoplasm Invasiveness
- Neoplasm Metastasis
- Adenocarcinoma
- Malignant Squamous Cell Neoplasm
- Malignant Paraganglionic Neoplasm
- Esophageal Neoplasms
- Colorectal Cancer
- Tissue Adhesions
- Malignant Neoplasm Of Breast
Interacting Proteins
- FANCD2
- MLH1
- PLXNB3
- YWHAZ
Pathways
- Cell Motility
- Cell Proliferation
- Cell Migration
- Cell Growth
- Localization
- Pathogenesis
- Cell Cycle
- Cell Adhesion
- Reverse Transcription
- Secretion
- Transport
- Fertilization
- Immune Response
PTMs
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FSCN1
bosterbio.com/bosterbio-gene-info-cards/FSCN1
References
PMID: 8068206 by Duh F.-M., et al. cDNA cloning and expression of the human homolog of the sea urchin fascin and Drosophila singed genes which encodes an actin-bundling protein.
PMID: 7933116 by Mosialos G., et al. Epstein-Barr virus infection induces expression in B lymphocytes of a novel gene encoding an evolutionarily conserved 55-kilodalton actin- bundling protein.
1 Publications of Boster Fascin Antibodies & ELISA Kits
- PubMed ID: 25231007, Jiang L, Wang P, Chen H. Ups J Med Sci. 2014 Nov;119(4):324-32. Doi: 10.3109/030...
*More publications can be found for each product on its corresponding product page