Protein fuzzy homolog Antibodies

AND Fuz ELISA kits, Protein fuzzy homolog Proteins

Many biological assays use antibodies to detect Protein fuzzy homolog, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Protein fuzzy homolog in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Protein fuzzy homolog antibodies...

We validate the specificity of these antibodies to Protein fuzzy homolog by testing them on tissues known to express Fuz positively and negatively. Browse below to find the Fuz antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Fuz Infographic by Boster Bio

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FUZ (NM_025129) Human Recombinant Protein

Coomassie blue staining of purified FUZ protein

$1249
Cat # PROTQ9BT04
20 µg

FUZ (NM_025129) Human Over-expression Lysate

Human

$628
Cat # LS080199
20 µg, 100 µg

Fuz Overview

Facts about Protein fuzzy homolog.

Protein fuzzy homolog (Fuz)

Probable planar cell polarity effector involved in cilium biogenesis. May regulate protein and membrane transport to the cilium.

Proposed to serve as core part of the CPLANE (ciliogenesis and planar polarity effectors) complex involved in the recruitment of peripheral IFT-A proteins into basal bodies (PubMed:19877275, PubMed:19767740, PubMed:27158779). May regulate the morphogenesis of hair follicles which depends on functional main cilia (PubMed:20962855).

Gene Information

Mouse
Gene Name:	Fuz
Uniprot:	Q3UYI6
Entrez:	70300

Family

Belongs to:

fuzzy family

Alternative Names

FLJ22688; fuzzy homolog (Drosophila); FY; protein fuzzy homolog

Molecular Weight

Mass (kDA):
45.588 kDA

Genomic Context


Mouse

Location:	7 B3\|7 28.99 cM
Sequence:	7;

Tissue Specificity

Expressed in dermal and epidermal cells.

Diseases

Congenital Abnormality
Exencephaly
Spina Bifida
Congenital Absence
Meningomyelocele
Anophthalmos
Craniofacial Abnormalities
Anencephaly
Cleft Palate

Neoplasms
Endocrine System Diseases
Hyperplasia

Pathways

Convergent Extension
Transport
Neural Tube Closure
Cell Proliferation
Tube Formation
Tube Closure
Filamentous Growth
Mating
Neural Tube Patterning
Intraflagellar Transport
Neural Tube Formation

Pathogenesis
Exocytosis
Mating Behavior
Meiosis
Secretion

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Fuz

References

PMID: 19877275 by Heydeck W., et al. Planar cell polarity effector gene Fuzzy regulates cilia formation and Hedgehog signal transduction in mouse.

PMID: 19767740 by Gray R.S., et al. The planar cell polarity effector Fuz is essential for targeted membrane trafficking, ciliogenesis and mouse embryonic development.