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- Table of Contents
GATA1 Antibodies
AND GATA1 ELISA kits, GATA1 Proteins
Many biological assays use antibodies to detect GATA1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GATA1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GATA1 antibodies...
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GATA1 Infographic by Boster Bio
All GATA1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA
$480
Cat # EKC1236
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1236
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2416
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2416
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2417
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2417
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A00408-3
100 μg/vial
Cat # A00408-3
100 μg/vial
GATA1 Overview
Facts about Erythroid transcription factor.
Erythroid transcription factor (GATA1)
Transcriptional activator or repressor which likely serves as a general change factor for erythroid development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of globin genes and of other genes expressed in erythroid cells.
Activates the transcription of genes involved in erythroid differentiation of K562 erythroleukemia cells, such as HBB, HBG1/2, ALAS2 and HMBS (PubMed:24245781). .
Gene Information
| Human | |
|---|---|
| Gene Name: | GATA1 |
| Uniprot: | P15976 |
| Entrez: | 2623 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
Eryf1; ERYF1GATA-binding protein 1 (globin transcription factor 1); GATA binding protein 1 (globin transcription factor 1); GATA1; GATA-1; GATA-1erythroid transcription factor; GATA-binding factor 1; GF-1; GF1globin transcription factor 1; NF-E1 DNA-binding protein; NFE1erythroid transcription factor 1; transcription factor GATA1; XLTT
Molecular Weight
Mass (kDA):
42.751 kDA
Genomic Context
| Human | |
|---|---|
| Location: | Xp11.23 |
| Sequence: | X; NC_000023.11 (48786540..48794311) |
Tissue Specificity
Erythrocytes.
Subcellular Localizations
Nucleus.
Diseases
- Leukemia
- Down Syndrome
- Anemia
- Acute Megakaryocytic Leukemias
- Acute Erythroblastic Leukemia
- Myeloproliferative Disease
- Myeloid Leukemia
- Myeloproliferative Syndrome, Transient
- Leukemia, Myelocytic, Acute
- Trisomy
- Malignant Neoplasms
- Neoplasms
- Leukemogenesis
Interacting Proteins
- CCDC24
- FHL3
- FRS3
- HEXIM2
- HOXA1
- KRTAP10-5
- KRTAP3-2
- KRTAP9-2
- LZTS2
- MDFI
Pathways
- Cell Differentiation
- Cell Cycle
- Pathogenesis
- Cell Development
- Cell Proliferation
- Localization
- Megakaryocyte Differentiation
- Methylation
- Translation
- Angiogenesis
- Cell Death
- Cell Growth
- Cell Maturation
PTMs
- Acetylation
- Phosphorylation
- Methylation
- Sumoylation
- Biotinylation
- Cleavage
Research Areas
- Stem Cell Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GATA1
bosterbio.com/bosterbio-gene-info-cards/GATA1
References
PMID: 2104960 by Trainor C.D., et al. Structure and evolution of a human erythroid transcription factor.
PMID: 2300555 by Zon L.I., et al. The major human erythroid DNA-binding protein (GF-1): primary sequence and localization of the gene to the X chromosome.
1 Publications of Boster GATA1 Antibodies & ELISA Kits
- PubMed ID: 30738249, Zhang J,Zhuang R,Zhang X,Hu W,Cheng K,Jiang D,Shen S,Zhang Y,Ding Y,Zhang Y.CD22...
*More publications can be found for each product on its corresponding product page