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- Table of Contents
GATA4 Antibodies
AND GATA4 ELISA kits, GATA4 Proteins
Many biological assays use antibodies to detect GATA4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GATA4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GATA4 antibodies...
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GATA4 Infographic by Boster Bio
All GATA4 Products
Product
Figures
Specificity
Applications
Price
Anti-GATA4 Rabbit Monoclonal Antibody
6 Citations 1 Q&As
Human, Mouse, Rat
Flow Cytometry, IF, ICC, WB
$370
Cat # M00499-1
100 μl
Cat # M00499-1
100 μl
Human, Mouse, Rat
ELISA
$480
Cat # EKC1237
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1237
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2259
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2259
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
Flow Cytometry, IF, ICC, WB
$405
Cat # A00499-2
100ul
Cat # A00499-2
100ul
Human, Mouse, Rat
IF, IHC, WB
$523
Cat # M00499-2
100 µl
Cat # M00499-2
100 µl
GATA4 Overview
Facts about Transcription factor GATA-4.
Transcription factor GATA-4 (GATA4)
Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3' and plays a key role in cardiac development and function (PubMed:24000169, PubMed:27984724). In collaboration with TBX5, it binds to cardiac super-enhancers and promotes cardiomyocyte gene expression, while it downregulates endocardial and endothelial gene expression (PubMed:27984724).
Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions (By similarity). Acts as a transcriptional activator of ANF in collaboration with NKX2-5 (By similarity).
Gene Information
| Human | |
|---|---|
| Gene Name: | GATA4 |
| Uniprot: | P43694 |
| Entrez: | 2626 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
GATA binding protein 4; GATA4; GATA-4; GATA-binding factor 4; GATA-binding protein 4; MGC126629; transcription factor GATA-4
Molecular Weight
Mass (kDA):
44.565 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 8p23.1 |
| Sequence: | 8; NC_000008.11 (11676931..11760002) |
Subcellular Localizations
Nucleus.
Diseases
- Hypertrophy
- Heart Diseases
- Congenital Heart Defects
- Cardiac Hypertrophy
- Neoplasms
- Heart Failure
- Congenital Heart Disease
- Heart Septal Defects
- Malignant Neoplasms
- Carcinoma
- Myocardial Infarction
- Infarction
- Congenital Abnormality
Interacting Proteins
- KLF13
- NKX2-5
Pathways
- Cell Differentiation
- Heart Development
- Pathogenesis
- Cell Proliferation
- Localization
- Methylation
- Secretion
- Cell Cycle
- Regeneration
- Sex Determination
- Translation
- Rna Interference
- Gastrulation
PTMs
- Phosphorylation
- Methylation
- Acetylation
- Cleavage
- Demethylation
- Dephosphorylation
Research Areas
- Mesenchymal Stem Cell Markers
- Stem Cell Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GATA4
bosterbio.com/bosterbio-gene-info-cards/GATA4
References
PMID: 7721094 by Huang W.Y., et al. Identification of a GATA motif in the cardiac alpha-myosin heavy- chain-encoding gene and isolation of a human GATA-4 cDNA.
PMID: 15734735 by Oskouian B., et al. Regulation of sphingosine-1-phosphate lyase gene expression by members of the GATA family of transcription factors.
3 Publications of Boster GATA4 Antibodies & ELISA Kits
- PubMed ID: 10.3892/mmr.2012.1185, Recombinant human brain natriuretic peptide therapy combined with bone mesenchym...
- PubMed ID: 24520255, Differentiation of human embryonic germ cells and transplantation in rats with a...
- PubMed ID: 23533594, Liu J, Wang Y, Du W, Liu W, Liu F, Zhang L, Zhang M, Hou M, Liu K, Zhang S, Yu B...
*More publications can be found for each product on its corresponding product page