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- Table of Contents
Facts about Glycoprotein hormone beta-5.
.
Human | |
---|---|
Gene Name: | GPHB5 |
Uniprot: | Q86YW7 |
Entrez: | 122876 |
Belongs to: |
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glycoprotein hormones subunit beta family |
Glycoprotein hormone beta-5
Mass (kDA):
14.232 kDA
Human | |
---|---|
Location: | 14q23.2 |
Sequence: | 14; NC_000014.9 (63312835..63318935, complement) |
Highly expressed in brain and at low levels in pituitary. Also found in retina, testis and skin but not in pancreas, parotid, kidney, stomach, liver, colon, small intestine, thyroid, brain or adrenal gland. In pituitary, colocalizes with ACTH, suggesting that it is located in corticotrophs.
Secreted.
PMID: 12045258 by Nakabayashi K., et al. Thyrostimulin, a heterodimer of two new human glycoprotein hormone subunits, activates the thyroid-stimulating hormone receptor.
PMID: 12089349 by Hsu S.Y., et al. Evolution of glycoprotein hormone subunit genes in bilateral metazoa: identification of two novel human glycoprotein hormone subunit family genes, GPA2 and GPB5.