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- Table of Contents
Facts about Immunoglobulin heavy variable 2-70D.
In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268).
Human | |
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Gene Name: | IGHV2-70D |
Uniprot: | A0A0C4DH43 |
Entrez: | 102723168 |
Belongs to: |
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No superfamily |
Immunoglobulin heavy variable 2-70D
Mass (kDA):
13.312 kDA
Human | |
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Location: | 14q32.33 |
Sequence: | 14; NC_000014.9 (106723574..106724017, complement) |
Secreted. Cell membrane.
PMID: 12508121 by Heilig R., et al. The DNA sequence and analysis of human chromosome 14.
PMID: 11340299 by Lefranc M.P.; Nomenclature of the human immunoglobulin heavy (IGH) genes.