- Table of Contents
We validate the specificity of these antibodies to MARK2 by testing them on tissues known to express MARK2 positively and negatively. Browse below to find the MARK2 antibody that suites your experiment. We have 6 of these antibodies and many publications and validation images.
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Facts about Serine/threonine-protein kinase MARK2.
Phosphorylates the microtubule-associated protein MAPT/TAU (PubMed:23666762). Plays a key role in cell polarity by phosphorylating the microtubule-associated proteins MAP2, MAP4 and MAPT/TAU at KXGS motifs, causing detachment from microtubules, and their disassembly.
|protein kinase superfamily|
EC 2.7.11; EC 220.127.116.11; ELKL motif kinase 1; ELKL motif kinase; EMK-1; EMK1PAR-1; MAP/microtubule affinity-regulating kinase 2MGC99619; PAR1 homolog; Par1b; Ser/Thr protein kinase PAR-1B; serine/threonine protein kinase EMK; serine/threonine-protein kinase MARK2
|Sequence:||11; NC_000011.10 (63838928..63911020)|
High levels of expression in heart, brain, skeletal muscle and pancreas, lower levels observed in lung, liver and kidney.
Cell membrane; Peripheral membrane protein. Cytoplasm. Lateral cell membrane. Cytoplasm, cytoskeleton. Cell projection, dendrite. Cytoplasm. Phosphorylation at Thr-596 by PRKCZ/aPKC and subsequent interaction with 14-3-3 protein YWHAZ promotes relocation from the cell membrane to the cytoplasm.