Meckel syndrome type 1 protein (MKS1)

Part of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Involved in centrosome migration to the apical cell surface during early ciliogenesis.

Required for ciliary structure and function, including a role in regulating length and proper amount through regulating centrosome duplication. Required for mobile branching morphology.