Nrarp Antibodies

AND Nrarp ELISA kits, Nrarp Proteins

Many biological assays use antibodies to detect Nrarp, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Nrarp in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Nrarp antibodies...

We validate the specificity of these antibodies to Nrarp by testing them on tissues known to express Nrarp positively and negatively. Browse below to find the Nrarp antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Nrarp Infographic by Boster Bio

All Nrarp Products

Product

Figures

Specificity

Applications

Price

Anti-NRARP Antibody

Human, Mouse

ELISA, WB

$380
Cat # A11207
100ul

NRARP (NM_001004354) Human Recombinant Protein

$1249
Cat # PROTQ7Z6K4
20 µg

Nrarp Overview

Facts about Notch-regulated ankyrin repeat-containing protein.

Notch-regulated ankyrin repeat-containing protein (Nrarp)

Involved in the regulation of liver cancer cells self-renewal (By similarity). Involved in the regulation of canonical Wnt signaling by stabilizing LEF1 (By similarity).

Involved in angiogenesis acting downstream of Notch at division points to modulate vascular density. Proposed to integrate endothelial Notch and Wnt signaling to control stem cell regeneration and to stablilize new endothelial connections during angiogenesis (PubMed:19154719).

Gene Information

Mouse
Gene Name:	Nrarp
Uniprot:	Q91ZA8
Entrez:	67122

Family

Belongs to:

NRARP family

Alternative Names

MGC61598; NOTCH-regulated ankyrin repeat protein; notch-regulated ankyrin repeat-containing protein; NRARP

Molecular Weight

Mass (kDA):
12.492 kDA

Genomic Context


Mouse

Location:	2\|2 A3
Sequence:	2;

Tissue Specificity

Expressed at high levels in the brain, heart, colon, kidney, liver, lung and small intestine. Expressed in retina, most prominent in endothelial cells at the migrating point of the vasculature behind leading tip cells. Expressed in testis.

Diseases

Neoplasms
Malignant Neoplasms
Adenoma
Hemangioma
Malignant Neoplasm Of Breast
Thymus Neoplasms
Thymoma
Malignant Tumor Of Colon
Hypoxia
Inflammatory Breast Carcinoma
Carcinoma

Tumor Angiogenesis
Lymphoma
Colorectal Cancer
Cell Invasion
Muscle Injury
Adenocarcinoma

Pathways

Notch Signaling Pathway
Somitogenesis
Segmentation
Regeneration
Cell Development
Muscle Hyperplasia
Angiogenesis

Chromatin Modification

PTMs

Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Nrarp

References

PMID: 11783997 by Krebs L.T., et al. The Nrarp gene encodes an ankyrin-repeat protein that is transcriptionally regulated by the notch signaling pathway.

PMID: 19268448 by Sewell W., et al. Cyclical expression of the Notch/Wnt regulator Nrarp requires modulation by Dll3 in somitogenesis.