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- Table of Contents
Facts about Ras-related C3 botulinum toxin substrate 3.
Promotes cell adhesion and spreading on fibrinogen in a CIB1 and alpha-IIb/beta3 integrin-mediated method. .
Human | |
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Gene Name: | RAC3 |
Uniprot: | P60763 |
Entrez: | 5881 |
Belongs to: |
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small GTPase superfamily |
p21-Rac3; ras-related C3 botulinum toxin substrate 3 (rho family, small GTP bindingprotein Rac3); ras-related C3 botulinum toxin substrate 3; rho family, small GTP binding protein Rac3
Mass (kDA):
21.379 kDA
Human | |
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Location: | 17q25.3 |
Sequence: | 17; NC_000017.11 (82031678..82034204) |
Highest levels in brain, also detected in heart, placenta and pancreas.
Cytoplasm. Endomembrane system. Cell projection, lamellipodium. Cytoplasm, perinuclear region. Cell membrane. Cytoplasm, cytoskeleton. Membrane-associated when activated. Colocalizes with NRBP to endomembranes and at the cell periphery in lamellipodia. Colocalized with CIB1 in the perinuclear area and at the cell periphery.
PMID: 9252344 by Haataja L., et al. Characterization of RAC3, a novel member of the Rho family.
PMID: 9852280 by Haataja L., et al. Identification of a novel Rac3-interacting protein C1D.