DNA-binding protein RFX6 Antibodies

AND RFX6 ELISA kits, DNA-binding protein RFX6 Proteins

Many biological assays use antibodies to detect DNA-binding protein RFX6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DNA-binding protein RFX6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DNA-binding protein RFX6 antibodies...

We validate the specificity of these antibodies to DNA-binding protein RFX6 by testing them on tissues known to express RFX6 positively and negatively. Browse below to find the RFX6 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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RFX6 Infographic by Boster Bio

All RFX6 Products

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Figures

Specificity

Applications

Price

RFXDC1 (RFX6) (NM_173560) Human Over-expression Lysate

Human

$628
Cat # LS222546
100 µg

RFX6 Overview

Facts about DNA-binding protein RFX6.

RFX6 3D structure. Source: alphafold

DNA-binding protein RFX6 (RFX6)

Transcription factor required to lead islet cell differentiation during endocrine pancreas development. Especially required for the differentiation of 4 of those 5 islet cell types and for the production of insulin (PubMed:20148032, PubMed:25497100).

Not required for pancreatic PP (polypeptide- producing) cells differentiation. Acts downstream of NEUROG3 and modulates the transcription factors involved in beta-cell maturation and function, thereby restricting the expression of this beta-cell differentiation and specification genes, and thus the beta-cell destiny choice.

Gene Information

Human
Gene Name:	RFX6
Uniprot:	Q8HWS3
Entrez:	222546

Family

Belongs to:

RFX family

Alternative Names

dJ955L16.1; DNA-binding protein RFX6; MGC33442; MTFS; Regulatory factor X 6; Regulatory factor X domain-containing protein 1; regulatory factor X, 6; RFX6; RFXDC1; RFXDC1regulatory factor X domain containing 1

Molecular Weight

Mass (kDA):
102.461 kDA

Genomic Context


Human

Location:	6q22.1
Sequence:	6; NC_000006.12 (116877218..116932163)

Tissue Specificity

Expressed in pancreas (PubMed:25497100). Expressed in pancreatic beta-cells (insulin-positive cells) and alpha-cells (glucagon-positive cells) (at protein level). Specifically expressed in pancreas, small intestine and colon (PubMed:20148032). Expressed in endocrine cells in the islets (PubMed:25497100).