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- Table of Contents
Facts about Reticulon-4 receptor-like 1.
Contributes to normal axon migration throughout the brain midline and regular formation of the corpus callosum. Protects motoneurons against apoptosis; protection against apoptosis is likely mediated by MAG.
Human | |
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Gene Name: | RTN4RL1 |
Uniprot: | Q86UN2 |
Entrez: | 146760 |
Belongs to: |
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Nogo receptor family |
Reticulon-4 receptor-like 1
Mass (kDA):
49.065 kDA
Human | |
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Location: | 17p13.3 |
Sequence: | 17; NC_000017.11 (1934677..2025334, complement) |
Predominantly expressed in brain. Expressed at lower levels in kidney, lung, mammary gland, placenta, salivary gland, skeletal muscle and spleen.
Cell membrane; Lipid-anchor, GPI-anchor. Membrane raft. Perikaryon. Cell projection. Localized to the surface of neurons, including axons.
PMID: 14664809 by Lauren J., et al. Two novel mammalian nogo receptor homologs differentially expressed in the central and peripheral nervous systems.
PMID: 12694398 by Pignot V., et al. Characterization of two novel proteins, NgRH1 and NgRH2, structurally and biochemically homologous to the Nogo-66 receptor.