RUSC1 Antibodies

AND RUSC1 ELISA kits, RUSC1 Proteins

Many biological assays use antibodies to detect RUSC1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RUSC1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RUSC1 antibodies...

We validate the specificity of these antibodies to RUSC1 by testing them on tissues known to express RUSC1 positively and negatively. Browse below to find the RUSC1 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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RUSC1 Infographic by Boster Bio

All RUSC1 Products

Product

Figures

Specificity

Applications

Price

Anti-RUSC1 Antibody

Human, Mouse, Rat

ELISA, WB

$449
Cat # A11204
0.1 mg

RUSC1 (NM_014328) Human Recombinant Protein

$1249
Cat # PROTQ9BVN2
20 µg

RUSC1 (NM_014328) Human Over-expression Lysate

Human

$628
Cat # LS023623
100 µg

C1orf104 (RUSC1-AS1) (NM_001039517) Human Over-expression Lysate

Human

$628
Cat # LS284618
100 µg

RUSC1 Overview

Facts about RUN and SH3 domain-containing protein 1.

RUSC1 3D structure. Source: alphafold

RUN and SH3 domain-containing protein 1 (RUSC1)

Putative signaling adapter which might play a role in neuronal differentiation. May be involved in regulation of NGF- dependent neurite outgrowth.

Proposed to play a role in neuronal vesicular trafficking, especially involving pre-synaptic membrane proteins. Seems to be involved in signaling pathways that are regulated by the prolonged activation of MAPK.

Gene Information

Human
Gene Name:	RUSC1
Uniprot:	Q9BVN2
Entrez:	23623

Family

Belongs to:

No superfamily

Alternative Names

DKFZp761A1822; Nesca; NESCARUN and SH3 domain-containing protein 1; New molecule containing SH3 at the carboxy-terminus; RUN and SH3 domain containing 1

Molecular Weight

Mass (kDA):
96.444 kDA

Genomic Context


Human

Location:	1q22
Sequence:	1; NC_000001.11 (155320894..155331118)

Tissue Specificity

Predominantly expressed in brain.

Subcellular Localizations

Cytoplasm. Nucleus. Cytoplasm, cytoskeleton. Cytoplasmic vesicle. Early endosome. Cell junction, synapse, postsynaptic density. Golgi apparatus. Translocated to the nuclear envelope upon stimulation with NGF. Associated with membranes and microtubules (By similarity).

Diseases

Bladder Neoplasm
Carcinoid Tumor
Malignant Neoplasms
Chondrosarcoma
Neoplasms
Parathyroid Neoplasms
Inflammation

Malignant Neoplasm Of Pancreas
Meningioma

Interacting Proteins

EXOSC8
FAM9B
IKBKG
PNMA1
RBPMS

STUB1
TRAF6
WWP2

Pathways

Localization
Transport
Cell Division
Glycosylation
Exocytosis

PTMs

Phosphorylation

Glycosylation

Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RUSC1

References

PMID: 10760598 by Matsuda S., et al. Molecular cloning and characterization of a novel human gene (NESCA) which encodes a putative adapter protein containing SH3.

PMID: 15024033 by MacDonald J.I.S., et al. Nesca, a novel adapter, translocates to the nuclear envelope and regulates neurotrophin-induced neurite outgrowth.