CBLC Antibodies

AND CBLC ELISA kits, CBLC Proteins

Many biological assays use antibodies to detect CBLC, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CBLC in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CBLC antibodies...

We validate the specificity of these antibodies to CBLC by testing them on tissues known to express CBLC positively and negatively. Browse below to find the CBLC antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CBLC Infographic by Boster Bio

All CBLC Products

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Product

Figures

Specificity

Applications

Price

Anti-Cbl-c Antibody

3 Q&As

Immunoprecipitation (right) and western blot (left) using Boster

Human

ELISA, IP, IHC, WB

$641
Cat # A03693
100ug

Anti-CBLC Antibody

Western blot analysis of extracts of various cells, using CBLC antibody

Immunofluorescence analysis of A549 cell using CBLC antibody

Human, Mouse

IF, WB

$405
Cat # A03693-1
100ul

Cbl c (CBLC) (NM_012116) Human Recombinant Protein

Coomassie blue staining of purified CBLC protein

$1062
Cat # PROTQ9ULV8
20 µg

Anti-Cbl c (CBLC) Mouse Monoclonal Antibody [Clone ID: OTI4E3]

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CBLC (Right lane) cDNA for 48 hrs and lysed

HEK293T cells transfected with either CBLC (Myc-DDK-tagged) overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-CBLC antibody (M03693)

Human

Flow Cytometry, WB

$523
Cat # M03693
100 µl

Cbl c (CBLC) (NM_012116) Human Over-expression Lysate

Cbl c (CBLC) Human Over-expression Lysates NM_001130852

Human

$628
Cat # LS023624
20 µg, 100 µg

CBLC Overview

Facts about E3 ubiquitin-protein ligase CBL-C.

CBLC 3D structure. Source: alphafold

E3 ubiquitin-protein ligase CBL-C (CBLC)

Acts as an E3 ubiquitin-protein ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and then transfers it to substrates promoting their degradation by the proteasome. Functionally coupled with the E2 ubiquitin-protein ligases UB2D1, UB2D2 and UB2D3.

Regulator of EGFR mediated signal transduction; upon EGF activation, ubiquitinates EGFR. Isoform 1, but not isoform 2, inhibits EGF stimulated MAPK1 activation.

Gene Information

Human
Gene Name:	CBLC
Uniprot:	Q9ULV8
Entrez:	23624

Family

Belongs to:

No superfamily

Alternative Names

Cas-Br-M (murine) ecotropic retroviral transforming sequence c; Cas-Br-M (murine) ectropic retroviral transforming sequence c; CBL3; CBL-3; CBL-SL; RING finger protein 57; RNF57SH3-binding protein CBL-3; SH3-binding protein CBL-C; signal transduction protein CBL-C