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- Table of Contents
Smoothened homolog Antibodies
AND SMO ELISA kits, Smoothened homolog Proteins
Many biological assays use antibodies to detect Smoothened homolog, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Smoothened homolog in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Smoothened homolog antibodies...
Designing a Western blot for Smoothened homolog? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the SMO Western Blot GuideSMO Infographic by Boster Bio
All SMO Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M01072-1
100 μl
Cat # M01072-1
100 μl
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M01072-3
100 μl
Cat # M01072-3
100 μl
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A05519-2
100 μg/vial
Cat # A05519-2
100 μg/vial
Human, Monkey, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A05530-1
100 μg/vial
Cat # A05530-1
100 μg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A05545-2
100 μg/vial
Cat # A05545-2
100 μg/vial
Human, Monkey, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, WB
$399
Cat # A01072
100μl
Cat # A01072
100μl
Human, Rat
ELISA, IF, IHC, ICC, WB
$370
Cat # A01697-2
100 μg/vial
Cat # A01697-2
100 μg/vial
Human, Mouse, Rat
IF, IHC, ICC, WB
$370
Cat # M08065-1
100 μl
Cat # M08065-1
100 μl
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A05520-2
100 µg/vial
Cat # A05520-2
100 µg/vial
Human, Mouse, Rat
IP, IF, ICC, WB
$370
Cat # M02425-1
100 μl/vial
Cat # M02425-1
100 μl/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A05519-1
100 μg/vial
Cat # A05519-1
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M01697
100 μl
Cat # M01697
100 μl
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M01077-1
100 μl/vial
Cat # M01077-1
100 μl/vial
Human, Mouse, Rat
IP, IF, IHC, ICC, WB
$370
Cat # M08133
100 μl/vial
Cat # M08133
100 μl/vial
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M08133-1
100 μl/vial
Cat # M08133-1
100 μl/vial
Human, Mouse, Rat
IF, IHC, ICC, WB
$370
Cat # M08090-1
100 μl/vial
Cat # M08090-1
100 μl/vial
Human, Mouse, Rat
Flow Cytometry, IP, IF, ICC, WB
$370
Cat # M08081-2
100 μl/vial
Cat # M08081-2
100 μl/vial
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M02424-2
100 μl/vial
Cat # M02424-2
100 μl/vial
Human, Mouse, Rat
IF, IHC, ICC, WB
$370
Cat # M02423-2
100 μl/vial
Cat # M02423-2
100 μl/vial
Human, Mouse, Rat
Flow Cytometry, IP, IF, ICC, WB
$370
Cat # M08071
100 μl
Cat # M08071
100 μl
Human, Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A00451-1
100 μg/vial
Cat # A00451-1
100 μg/vial
Human, Mouse, Rat
IF, IHC, WB
$405
Cat # A05066-1
100ul
Cat # A05066-1
100ul
Human, Mouse, Rat
ELISA, IP, IF, IHC, WB
$146
Cat # M01072-5
20μL, 40μL, 100μL, 200μL
Cat # M01072-5
20μL, 40μL, 100μL, 200μL
Human, Mouse, Rat
ELISA
$480
Cat # EKC1325
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1325
1 kit, containing one 96-well plate and all necessary reagents
Human
$628
Cat # LS000059
20 µg, 100 µg
Cat # LS000059
20 µg, 100 µg
Human, Mouse, Rat
ELISA
$480
Cat # EKC1015
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1015
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2164
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2164
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2425
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2425
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2057
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2057
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse
ELISA
$480
Cat # EKC1848
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1848
1 kit, containing one 96-well plate and all necessary reagents
Human
ELISA
$480
Cat # EKC1814
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1814
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse, Rat
ELISA
$480
Cat # EKC1397
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1397
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse, Rat
ELISA
$480
Cat # EKC1336
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1336
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse, Rat
ELISA
$480
Cat # EKC1287
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1287
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse, Rat
ELISA
$480
Cat # EKC1163
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1163
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse, Rat
ELISA
$480
Cat # EKC1073
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1073
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse, Rat
ELISA
$480
Cat # EKC1017
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1017
1 kit, containing one 96-well plate and all necessary reagents
Human
$960
Cat # LS004629
20 µg, 100 µg
Cat # LS004629
20 µg, 100 µg
Human, Mouse, Rat
IF, IHC, IHC-F, WB
$370
Cat # M01072-7
100 μg/vial
Cat # M01072-7
100 μg/vial
Human, Mouse, Rabbit
IHC, WB
$370
Cat # M04578-3
100 μg/vial
Cat # M04578-3
100 μg/vial
Chicken, Human, Turkey
IHC, ICC, WB
$370
Cat # M08680-2
100 μg/vial
Cat # M08680-2
100 μg/vial
Chicken, Human, Mouse, Rat
IHC, WB
$370
Cat # M02014-6
100 μg/vial
Cat # M02014-6
100 μg/vial
Human, Mouse, Rat
ELISA
$480
Cat # EKC1509
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1509
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse
ELISA
$480
Cat # EKC1447
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1447
1 kit, containing one 96-well plate and all necessary reagents
SMO Overview
Facts about Smoothened homolog.
Smoothened homolog (SMO)
G protein-coupled receptor which probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. Binding of sonic hedgehog (SHH) to its receptor patched is considered to prevent normal inhibition by patched of smoothened (SMO).
Required for the accumulation of KIF7, GLI2 and GLI3 in the cilia (PubMed:19592253). Interacts with DLG5 at the ciliary base to induce the accumulation of KIF7 and GLI2 at the ciliary idea for GLI2 activation (By similarity).
Gene Information
| Human | |
|---|---|
| Gene Name: | SMO |
| Uniprot: | Q99835 |
| Entrez: | 6608 |
Family
| Belongs to: |
|---|
| G-protein coupled receptor Fz/Smo family |
Alternative Names
bnb; CRJS; FZD11; Gx; Protein Gx; SMO; SMOH; SMOHseven transmembrane helix receptor; smoothened (Drosophila) homolog; smoothened homolog (Drosophila); smoothened homolog; Smoothened
Molecular Weight
Mass (kDA):
86.397 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 7q32.1 |
| Sequence: | 7; NC_000007.14 (129188633..129213548) |
Subcellular Localizations
Membrane; Multi-pass membrane protein. Cell projection, cilium.
Diseases
- Malignant Neoplasms
- Neoplasms
- Carcinoma
- Basal Cell Carcinoma
- Cell Transformation, Neoplastic
- Medulloblastoma
- Skin Neoplasms
- Carcinogenesis
- Malignant Neoplasm Of Pancreas
- Malignant Paraganglionic Neoplasm
- Basal Cell Nevus Syndrome
- Neoplasm Metastasis
Pathways
- Cell Proliferation
- Localization
- Cell Growth
- Transport
- Pathogenesis
- Cell Death
- Cell Cycle
- Regeneration
- Intraflagellar Transport
- Cell Differentiation
- Neurogenesis
- Angiogenesis
- Secretion
PTMs
- Phosphorylation
- Oxidation
- Acetylation
- Cleavage
- Methylation
Research Areas
- GPCR
- Growth and Development
- Neuronal Cell Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SMO
bosterbio.com/bosterbio-gene-info-cards/SMO
References
PMID: 8906787 by Stone D.M., et al. The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog.
PMID: 9422511 by Xie J., et al. Activating Smoothened mutations in sporadic basal-cell carcinoma.
142 Publications of Boster Smoothened homolog Antibodies & ELISA Kits
- PubMed ID: 10.3967/bes2017.086, Crystalline Silica Promotes Rat Fibrocyte Differentiation in Vitro, and Fibrocyt...
- PubMed ID: 10.3760/cma.j.issn.0366-6999.2009.03.016, Mast cell degranulator compound 48–80 promotes atherosclerotic plaque in apoli...
- PubMed ID: 10.1620/tjem.218.25, Endothelial Cell Apoptosis is Responsible for the Formation of Coronary Thrombot...
- PubMed ID: 10.1161/JAHA.120.017094, Extreme Diversity of the Human Vascular Mesenchymal Cell Landscape
- PubMed ID: 10.1089/jmf.2018.4364, Naringin and Naringenin Relax Rat Tracheal Smooth by Regulating BKCa Activation
- PubMed ID: 10.1080/1028602042000325609, Effects of isoliensinine on angiotensin II-induced proliferation of porcine coro...
- PubMed ID: 10.1042/BSR20181504, The deregulation of STIM1 and store operative calcium entry impaired aortic smoo...
- PubMed ID: 10.1016/j.tox.2017.04.001, The induction of cytochrome P450 2E1 by ethanol leads to the loss of synaptic pr...
- PubMed ID: 10.1016/j.placenta.2020.07.007, Heme oxygenase-1 gene modified human placental mesenchymal stem cells promote pl...
- PubMed ID: 10.1016/j.mce.2017.11.004, Estrogen receptor beta maintains expression of KLF15 to prevent cardiac myocyte ...
- PubMed ID: 10.1016/j.cellsig.2019.109387, MeCP2 triggers diabetic cardiomyopathy and cardiac fibroblast proliferation by i...
- PubMed ID: 10.1016/j.biopha.2019.109586, Tanshinone IIA attenuates silica-induced pulmonary fibrosis via inhibition of TG...
- PubMed ID: 10.1016/j.biomaterials.2021.121260, An improved osseointegration of metal implants by pitavastatin loaded multilayer...
- PubMed ID: 10.1016/j.actbio.2019.10.011, Biomimetic hydrogel for rapid and scar-free healing of skin wounds inspired by t...
- PubMed ID: 10.1007/s10620-009-0743-2, The GABAB Receptor Inhibits Activation of Hepatic Stellate Cells
- PubMed ID: 30476735, Chang C,Li K,Jiang S,Li B,Cao L,Wang P.Downregulation of TRPC6 expression is a c...
- PubMed ID: 30888602, Wei X,Bao Y,Zhan X,Zhang L,Hao G,Zhou J,Chen Q.MiR-200a ameliorates peritoneal f...
- PubMed ID: 31404347, Ba P,Zhang X,Yu M,Li L,Duan X,Wang M,Lv S, Fu G,Yang P,Yang C,Sun Q.Cancer assoc...
- PubMed ID: 30787984, Xu M,Lv J,Wang P,Liao Y,Li Y,Zhao W,Zen J,Dong Z,Guo Z,Bo X,Liu M,Zhang L,Hu G,C...
- PubMed ID: 30462533, Yang YL,Hu F,Xue M,Jia YJ,Zheng ZJ,Li Y,Xue YM.Early growth response protein-1 u...
- PubMed ID: 31595443, Fang X,Hu X,Zheng Z,Tao K,Wang H,Guan H,Shi J,Ji P,Cai W,Bai X,Zhu X,Han J,Liu J...
*Showing only the more recent 20. More publications can be found for each product on its corresponding product page