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Product Info Summary
| SKU: | A00451 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human, Mouse |
| Host: | Rabbit |
| Application: | WB |
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Product info
Product Name
Anti-Smoothened homolog SMO Antibody
View all Smoothened Antibodies
SKU/Catalog Number
A00451
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Smoothened homolog SMO Antibody catalog # A00451. Tested in WB applications. This antibody reacts with Human,Mouse.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Smoothened homolog SMO Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00451)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human Insulin R around the phosphorylation site of Y1361.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A00451 is reactive to SMO in Human, Mouse
Applications
A00451 is guaranteed for WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
86.397kDa
Background of Smoothened
This antibody is suitable for Cancer, Immunology and Nuclear Signaling research. Fibroblast Activation Protein (FAP) is expressed in the stroma of sites that are undergoing wound healing. In addition, it has recently been reported that FAP is expressed in the stroma of sites of metastatic disease. Inhibition of FAP may lead to a dramatic decrease in the number of metastatic osteosarcoma lung nodules. FAP exists as an inactive monomer and when activated forms homodimers or heterodimers with DPP4. Multiple isoforms of FAP are reported as alternative splicing products from a common gene.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:2000
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
Protein Target Info & Infographic
Gene/Protein Information For SMO (Source: Uniprot.org, NCBI)
Gene Name
SMO
Full Name
Smoothened homolog
Weight
86.397kDa
Superfamily
G-protein coupled receptor Fz/Smo family
Alternative Names
bnb; CRJS; FZD11; Gx; Protein Gx; SMO; SMOH; SMOHseven transmembrane helix receptor; smoothened (Drosophila) homolog; smoothened homolog (Drosophila); smoothened homolog; Smoothened SMO CRJS, FZD11, Gx, PHLSH, SMO smoothened, frizzled class receptor smoothened homolog|frizzled family member 11|protein Gx|seven transmembrane helix receptor|smoothened, frizzled family receptor|smoothened, seven transmembrane spanning receptor
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on SMO, check out the SMO Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for SMO: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Smoothened homolog SMO Antibody (A00451)
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No publications found for A00451
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