THO complex subunit 6 homolog (Thoc6)

Acts as part of the THO subcomplex of the TREX complex that's thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA rather than with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent way to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm through the TAP/NFX1 pathway.

Plays a role in apoptosis negative control involved in brain development (By similarity). .