TRPC5 Antibodies

AND TRPC5 ELISA kits, TRPC5 Proteins

Many biological assays use antibodies to detect TRPC5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TRPC5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TRPC5 antibodies...

We validate the specificity of these antibodies to TRPC5 by testing them on tissues known to express TRPC5 positively and negatively. Browse below to find the TRPC5 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TRPC5 Infographic by Boster Bio

All TRPC5 Products

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Specificity

Applications

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Anti-TRPC5 Antibody Picoband®

4 Q&As

Anti-TRPC5 Picoband antibody, PB9271, Western blottingAll lanes: Anti TRPC5 (PB9271) at 0

Western blot analysis of TRPC5 using anti-TRPC5 antibody (PB9271)

Human

$370
Cat # PB9271
100 μg/vial

Anti-TRPC5 Antibody Picoband®

Western blot analysis of TRPC5 using anti-TRPC5 antibody (A02701)

Human, Mouse, Rat

ELISA, WB

$370
Cat # A02701
100 μg/vial

Anti-TRPC5 Antibody

Western blot analysis of extracts of various cell lines, using TRPC5 antibody at 1:1000 dilution

Immunofluorescence analysis of Neuro-2a cells using TRPC5 Rabbit pAb at dilution of 1:150

Immunofluorescence analysis of SH-SY5Y cells using TRPC5 Rabbit pAb at dilution of 1:150

Human, Mouse, Rat

IF, ICC, WB

$405
Cat # A02701-1
100ul

TRPC5 (NM_012471) Human Over-expression Lysate

Human

$960
Cat # LS007224
20 µg, 100 µg

TRPC5 Overview

Facts about Short transient receptor potential channel 5.

TRPC5 3D structure. Source: alphafold

Short transient receptor potential channel 5 (TRPC5)

Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors.

Has also been shown to be calcium-selective (By similarity). May also be activated by intracellular calcium store depletion.

Gene Information

Human
Gene Name:	TRPC5
Uniprot:	Q9UL62
Entrez:	7224

Family

Belongs to:

transient receptor (TC 1.A.4) family

Alternative Names

hTRP5; hTRP-5; short transient receptor potential channel 5; transient receptor potential cation channel, subfamily C, member 5; Transient receptor protein 5; TRP-5; TRP5transient receptor potential channel 5; TrpC5

Molecular Weight

Mass (kDA):
111.412 kDA

Genomic Context


Human

Location:	Xq23
Sequence:	X; NC_000023.11 (111774314..112082943, complement)

Tissue Specificity

Expressed in brain with higher levels in fetal brain. Found in cerebellum and occipital pole.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

Hypertensive Disease
Nervousness
Hypoxia
Asthma
Columnar Cell Hyperplasia Of The Breast
Pain
Diabetes Mellitus
Inflammation
Pertussis
Pathologic Vasoconstriction
Hypertrophy
Atherosclerosis

Acidosis
Neoplasms
Cardiovascular Diseases
Ischemia
Diabetes Mellitus, Non-insulin-dependent
Autoimmune Reaction
Essential Hypertension

Pathways

Localization
Secretion
Cell Proliferation
Store-operated Calcium Entry
Rna Interference
Transport
Cell Migration
Vasoconstriction
Synaptic Transmission
Cell Differentiation
Gene Silencing
Neuroprotection
Cell Activation

Catecholamine Secretion
Cell Motility
Lactation
Cellular Localization
Muscle Contraction
Membrane Depolarization
Cell Death

PTMs

Phosphorylation
Biotinylation

Cleavage
Nitrosylation

Hydroxylation

Research Areas

Breast Cancer
Cancer

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TRPC5

References

PMID: 10493832 by Sossey-Alaoui K., et al. Molecular cloning and characterization of TRPC5 (HTRP5), the human homologue of a mouse brain receptor-activated capacitative Ca(2+) entry channel.

PMID: 9687496 by Philipp S., et al. A novel capacitative calcium entry channel expressed in excitable cells.