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- Table of Contents
TRPS1 Antibodies
AND TRPS1 ELISA kits, TRPS1 Proteins
Many biological assays use antibodies to detect TRPS1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TRPS1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TRPS1 antibodies...
Designing an IHC experiment for TRPS1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the TRPS1 IHC GuideTRPS1 Infographic by Boster Bio
All TRPS1 Products
Product
Figures
Specificity
Applications
Price
Human
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A02328-2
100 μg/vial
Cat # A02328-2
100 μg/vial
TRPS1 Overview
Facts about Zinc finger transcription factor Trps1.
Zinc finger transcription factor Trps1 (TRPS1)
Transcriptional repressor. Binds specifically to GATA sequences and represses expression of GATA-regulated genes in selected sites and stages in vertebrate development.
Regulates chondrocyte proliferation and differentiation. Executes multiple functions in proliferating chondrocytes, expanding the region of distal chondrocytes, activating proliferation in columnar cells and supporting the distinction of columnar into hypertrophic chondrocytes.
Gene Information
| Human | |
|---|---|
| Gene Name: | TRPS1 |
| Uniprot: | Q9UHF7 |
| Entrez: | 7227 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
GC79; trichorhinophalangeal syndrome I; tricho-rhino-phalangeal syndrome type I protein; TRPS1
Molecular Weight
Mass (kDA):
141.521 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 8q23.3 |
| Sequence: | 8; NC_000008.11 (115408496..115668975, complement) |
Tissue Specificity
Ubiquitously expressed in the adult. Found in fetal brain, lung, kidney, liver, spleen and thymus. More highly expressed in androgen-dependent than in androgen-independent prostate cancer cells.
Subcellular Localizations
Nucleus.
Diseases
- Langer-giedion Syndrome
- Malignant Neoplasms
- Dwarfism
- Craniofacial Abnormalities
- Malignant Neoplasm Of Prostate
- Malignant Neoplasm Of Breast
- Trichorhinophalangeal Dysplasia Type I
- Mammary Neoplasms
- Osteochondrodysplasias
- Neoplasms
- Dysplasia
- Prostatic Neoplasms
Interacting Proteins
- RNF4
Pathways
- Cell Migration
- Chondrocyte Differentiation
- Localization
- Transport
- Osteoblast Differentiation
- Chondrocyte Proliferation
- Translation
- Cell Differentiation
- Cell Death
- Hair Follicle Morphogenesis
- Cell Activation
- Gene Silencing
- Programmed Cell Death
PTMs
- Phosphorylation
- Sumoylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TRPS1
bosterbio.com/bosterbio-gene-info-cards/TRPS1
References
PMID: 10615131 by Momeni P., et al. Mutations in a new gene, encoding a zinc-finger protein, cause tricho-rhino-phalangeal syndrome type I.
PMID: 10974077 by Chang G.T.G., et al. Characterization of a zinc-finger protein and its association with apoptosis in prostate cancer cells.