Ufm1-specific protease 2 Antibodies

AND UFSP2 ELISA kits, Ufm1-specific protease 2 Proteins

Many biological assays use antibodies to detect Ufm1-specific protease 2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Ufm1-specific protease 2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Ufm1-specific protease 2 antibodies...

We validate the specificity of these antibodies to Ufm1-specific protease 2 by testing them on tissues known to express UFSP2 positively and negatively. Browse below to find the UFSP2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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UFSP2 Infographic by Boster Bio

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UFSP2 (NM_018359) Human Over-expression Lysate

Human

$628
Cat # LS055325
20 µg, 100 µg

UFSP2 Overview

Facts about Ufm1-specific protease 2.

UFSP2 3D structure. Source: alphafold

Ufm1-specific protease 2 (UFSP2)

Thiol protease which recognizes and hydrolyzes the peptide bond at the C-terminal Gly of UFM1, a ubiquitin-like modifier protein bound to a number of target proteins. Doesn't hydrolyze SUMO1 or ISG15 ubiquitin-like proteins.

During TRIP4 deufmylation may regulate intracellular nuclear receptors transactivation and thereby regulate cell proliferation and differentiation. .

Gene Information

Human
Gene Name:	UFSP2
Uniprot:	Q9NUQ7
Entrez:	55325

Family

Belongs to:

peptidase C78 family

Alternative Names

FLJ11200; UFM1-specific peptidase 2; ufm1-specific protease 2

Molecular Weight

Mass (kDA):
53.261 kDA

Genomic Context


Human

Location:	4q35.1
Sequence:	4; NC_000004.12 (185399537..185425985, complement)

Subcellular Localizations

Cytoplasm. Endoplasmic reticulum. Nucleus.

Diseases

Dysplasia
Glaucoma, Open-angle
Glaucoma
Hip Dislocation, Congenital
Blind Vision
Primary Open Angle Glaucoma

Pathways

Conjugation

PTMs

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/UFSP2

References

PMID: 25219498 by Yoo H.M., et al. Modification of ASC1 by UFM1 is crucial for ERalpha transactivation and breast cancer development.

PMID: 25732826 by Aksnes H., et al. An organellar nalpha-acetyltransferase, naa60, acetylates cytosolic N termini of transmembrane proteins and maintains Golgi integrity.