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Product Info Summary
| SKU: | A09776 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Chicken |
| Application: | ELISA, WB |
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Product info
Product Name
Anti-ECRG1 TMPRSS11A Antibody
SKU/Catalog Number
A09776
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-ECRG1 TMPRSS11A Antibody (Catalog # A09776). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
ECRG1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-ECRG1 TMPRSS11A Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A09776)
Host
Chicken
Contents
ECRG1 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgY
Immunogen
ECRG1 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human ECRG1. The immunogen is located within amino acids 300 - 350 of ECRG1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
At least two isoforms of ECRG1 are known to exist; ECRG1 antibody is predicted to not cross-react with other ECRG family members.
Reactive Species
A09776 is reactive to Tmprss11a in Human, Mouse, Rat
Applications
A09776 is guaranteed for ELISA, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
43.605kDa
Background of Tmprss11a
Epidermal type-II transmembrane serine protease (ECRG1), also known as TMPRSS11A, is a member of a novel esophageal cancer-related gene family. It is a type-II transmembrane serine protease which may play a role in cellular senescence. It is expressed in esophagus, liver, colon and lung. Overexpression of ECRG1 inhibits cell growth and induces G1 cell cycle arrest. It is down-regulated in esophagus cancers (EC) and might play important roles in the initiation and progression of EC.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
ECRG1 antibody can be used for detection of ECRG1 by Western blot at 1 μg/mL.
Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of ECRG1 in mouse liver tissue lysate with ECRG1 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.
Protein Target Info & Infographic
Gene/Protein Information For Tmprss11a (Source: Uniprot.org, NCBI)
Gene Name
Tmprss11a
Full Name
Transmembrane protease serine 11A
Weight
43.605kDa
Superfamily
peptidase S1 family
Alternative Names
Airway Trypsin-Like Protease 1; EC 3.4.21; EC 3.4.21.; ECRG1; Epidermal Type II Transmembrane Serine Protease; Epidermal Type-II Transmembrane Serine Protease; Esophageal Cancer-Susceptibility Gene 1 Protein; HATL1; HESP; Transmembrane Protease Serine 11A; Transmembrane Protease, Serine 11A
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on Tmprss11a, check out the Tmprss11a Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for Tmprss11a: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-ECRG1 TMPRSS11A Antibody (A09776)
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No publications found for A09776
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