Product Info Summary
SKU: | A03894-2 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | Flow Cytometry, IHC, WB |
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Product info
Product Name
Anti-Laminin Beta 1 LAMB1 Antibody
View all Laminin beta 1 Antibodies
SKU/Catalog Number
A03894-2
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Laminin Beta 1 LAMB1 Antibody catalog # A03894-2. Tested in WB,IHC,Flow Cytometry applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Laminin Beta 1 LAMB1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03894-2)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from C-terminal of human LAMB1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A03894-2 is reactive to LAMB1 in Human, Mouse, Rat
Applications
A03894-2 is guaranteed for Flow Cytometry, IHC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
198.038kDa
Background of Laminin beta 1
Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Involved in the organization of the laminar architecture of cerebral cortex. It is probably required for the integrity of the basement membrane/glia limitans that serves as an anchor point for the endfeet of radial glial cells and as a physical barrier to migrating neurons. Radial glial cells play a central role in cerebral cortical development, where they act both as the proliferative unit of the cerebral cortex and a scaffold for neurons migrating toward the pial surface.
Vuolteenaho R., J. Biol. Chem. 265:15611-15616(1990).
Pikkarainen T., J. Biol. Chem. 262:10454-10462(1987).
Scherer S.W., Science 300:767-772(2003).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:1,000
FC: 1:50-1:100
IHC: 1:100-1:500
Validation Images & Assay Conditions
Click image to see more details
Figure 1. Immunohistochemistry validation of LAMB1 using Anti-Laminin Beta 1 LAMB1 Antibody (A03894-2).
Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-Laminin beta 1 antibody. Counter stained with hematoxylin.For more protocol information of IHC
Click image to see more details
Figure 2. Immunohistochemistry validation of LAMB1 using Anti-Laminin Beta 1 LAMB1 Antibody (A03894-2).
Immunohistochemical analysis of paraffin-embedded mouse colon tissue using anti-Laminin beta 1 antibody. Counter stained with hematoxylin.For more protocol information of IHC
Protein Target Info & Infographic
Gene/Protein Information For LAMB1 (Source: Uniprot.org, NCBI)
Gene Name
LAMB1
Full Name
Laminin subunit beta-1
Weight
198.038kDa
Alternative Names
CLM; cutis laxa with marfanoid phenotype; Laminin B1 chain; laminin subunit beta-1; laminin, beta 1; Laminin-1 subunit beta; Laminin-10 subunit beta; Laminin-12 subunit beta; Laminin-2 subunit beta; Laminin-6 subunit beta; Laminin-8 subunit beta; MGC142015 LAMB1 CLM, LIS5 laminin subunit beta 1 laminin subunit beta-1|laminin B1 chain|laminin, beta 1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on LAMB1, check out the LAMB1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for LAMB1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Laminin Beta 1 LAMB1 Antibody (A03894-2)
Hello CJ!
A03894-2 has been cited in 1 publications:
*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.
Na,L.,Q,B.,Xiumei,Z.et al.Research into the intervention effect of folic acid on arsenic-induced heart abnormalities in fetal rats during the periconception period.BMC Cardiovasc Disord 20, 139 (2020).https://doi.org/10.1186/s12872-020-01418-z
Species: Rat
A03894-2 usage in article: APP:WB, SAMPLE:HEART TISSUE, DILUTION:NA
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